melanosomen.
/ˈmɛlənə(ʊ)səʊm/, /mᵻˈlanəsəʊm/, U.S. /ˈmɛlənoʊˌsoʊm/, /ˈmɛlənəˌsoʊm/, /məˈlænoʊˌsoʊm/, /məˈlænəˌsoʊm/ Physiology.
An organelle of melanocytes in which melanin is synthesized and stored.
ΘΚΠ
the world > life > biology > substance > cell > cell organelle or contents > [noun] > other organelles or contents
raphide1831
body1839
raphid1863
mucigen1874
cell sap1875
globoid1875
raphis1879
pyrenoid1883
mucinogen1884
plastid1885
molluscum corpuscle1886
hyalosome1889
molluscum body1892
statolith1892
dictyosome1893
centrosome1895
Nissl body1898
Nissl granule1898
Nissl substance1899
archespore1901
blepharoplast1907
liposome1910
statocone1910
kinetosome1912
Golgi body1916
kinetoplast1925
lipochondrion1936
microsome1943
kappa1945
Pappenheimer body1947
microbody1954
lysosome1955
siderosome1957
ribosome1958
melanosome1961
cisterna1962
microtubule1962
plasmalemmasome1962
phagolysosome1963
informosome1964
monosome1964
mucocyst1965
peroxisome1965
rhoptry1967
spectrin1968
virosome1970
1961 M. Seiji et al. in Jrnl. Investigative Dermatol. 36 251/2 Because the melanin granule has been shown by electronmicroscopy to be structurally distinct from mitochondria, to be unique in its localization within the cytoplasm of mammalian melanocytes, and to contain a specialized metabolic pathway that converts tyrosine to melanin, we would like to suggest that during its enzymically active stages it be called a melanosome... The term ‘melanin granule’ could be reserved for the mature, fully melanized particle which has lost its tyrosinase activity and is no longer confined to the cytoplasm of the melanocyte.
1973 Nature 26 Oct. 436/3 The melanocyte's contribution [to pigmentation] begins with the synthesis of melanosomes, and the oxidation of tyrosine to melanin.
1989 Jrnl. Royal Soc. Med. 82 539/1 Melanogenesis is restricted to the melanosomes, controlled by tyrosinase, and postdopa-oxidase regulators.
This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022).
<
n.1961