melatoninn.

Brit.

/ˌmɛləˈtəʊnɪn/, U.S.

/ˌmɛləˈtoʊnən/

Origin: A borrowing from Greek, combined with an English element. Etymons: Greek μέλας , serotonin n.

Etymology: < ancient Greek μέλας black (see melano- comb. form) + -tonin (in serotonin n.).

Physiology.

A hormone, synthesized from serotonin by cells of the pineal gland and retina, which opposes the effect of MSH (melanocyte-stimulating hormone) and may play a role in regulating photoperiodic rhythms; N-acetyl-5-methoxytryptamine, CH₃O·C₈H₅N·CH₂·CH₂·NH·CO·CH₃.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > hormone > [noun] > other hormones

thyro-iodine1896

parathormone1925

parathyroid hormone1925

oestrin1926

oestrogen1927

relaxin1930

theelin1930

prolan1931

galactin1932

inhibin1932

prolactin1932

oestriol1933

oestrone1933

oestradiol1934

adrenocorticotrophin1943

pancreozymin1943

ADH1945

adrenocorticotropin1945

cortisone1949

mineralocorticoid1950

electrocortin1953

aldosterone1954

angiotensin1958

melatonin1958

calcitonin1961

zeranol1971

amylin1988

adiponectin1999

adipokine2001

1958 A. B. Lerner et al. in Jrnl. Amer. Chem. Soc. 80 2587/1 We wish to report isolation from beef pineal glands of the active factor that can lighten skin color and inhibit MSH. It is suggested that this substance be called melatonin.

1965 Sci. Amer. July 60/3 The ability of melatonin to modify gonadal function suggests, but does not prove, that its secretion may have something to do with the timing of the estrus and menstrual cycles.

1968 R. Passmore & J. S. Robson Compan. Med. Stud. I. xxiv. 36/1 Production of melatonin falls when a rat is in a constantly lit environment... How far these findings relate to man is uncertain; but secreting tumours of the pineal in children lead to delayed sexual development, as if too much melatonin were being released.

1970 Nature 30 May 804/1 Melatonin controls diurnal and seasonal adjustments of activity in many species.

1994 Daily Tel. 2 Mar. 8/8 The study marks an important step in testing melatonin as a sleeping pill.

This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022).

单词	melatonin
释义	melatoninn. Brit. /ˌmɛləˈtəʊnɪn/, U.S. /ˌmɛləˈtoʊnən/ Origin: A borrowing from Greek, combined with an English element. Etymons: Greek μέλας , serotonin n. Etymology: < ancient Greek μέλας black (see melano- comb. form) + -tonin (in serotonin n.). Physiology. A hormone, synthesized from serotonin by cells of the pineal gland and retina, which opposes the effect of MSH (melanocyte-stimulating hormone) and may play a role in regulating photoperiodic rhythms; N-acetyl-5-methoxytryptamine, CH₃O·C₈H₅N·CH₂·CH₂·NH·CO·CH₃. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > hormone > [noun] > other hormones thyro-iodine1896 parathormone1925 parathyroid hormone1925 oestrin1926 oestrogen1927 relaxin1930 theelin1930 prolan1931 galactin1932 inhibin1932 prolactin1932 oestriol1933 oestrone1933 oestradiol1934 adrenocorticotrophin1943 pancreozymin1943 ADH1945 adrenocorticotropin1945 cortisone1949 mineralocorticoid1950 electrocortin1953 aldosterone1954 angiotensin1958 melatonin1958 calcitonin1961 zeranol1971 amylin1988 adiponectin1999 adipokine2001 1958 A. B. Lerner et al. in Jrnl. Amer. Chem. Soc. 80 2587/1 We wish to report isolation from beef pineal glands of the active factor that can lighten skin color and inhibit MSH. It is suggested that this substance be called melatonin. 1965 Sci. Amer. July 60/3 The ability of melatonin to modify gonadal function suggests, but does not prove, that its secretion may have something to do with the timing of the estrus and menstrual cycles. 1968 R. Passmore & J. S. Robson Compan. Med. Stud. I. xxiv. 36/1 Production of melatonin falls when a rat is in a constantly lit environment... How far these findings relate to man is uncertain; but secreting tumours of the pineal in children lead to delayed sexual development, as if too much melatonin were being released. 1970 Nature 30 May 804/1 Melatonin controls diurnal and seasonal adjustments of activity in many species. 1994 Daily Tel. 2 Mar. 8/8 The study marks an important step in testing melatonin as a sleeping pill. This entry has been updated (OED Third Edition, June 2001; most recently modified version published online March 2022). < n.1958
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