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单词 metformin
释义

metforminn.

Brit. /mɛtˈfɔːmɪn/, U.S. /mɛtˈfɔrmɪn/
Origin: Formed within English, by compounding. Etymons: methyl n., phenformin n.
Etymology: < met- (in methyl n.) + -formin (in phenformin n.).
Pharmacology.
A biguanide derivative, C4H11N5, used, now chiefly as the hydrochloride, as an oral hypoglycaemic agent in the treatment of type 2 diabetes mellitus; 1,1-dimethylbiguanide.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for diabetes
synthalin1927
protamine insulin1935
protamine zinc insulin1935
Ultralente1953
sulphonylurea1956
tolbutamide1956
phenformin1959
acetohexamide1961
metformin1961
tolazamide1963
1961 Lancet 24 June 1368/1 Effectiveness and better gastrointestinal tolerance have been claimed for dimethyldiguanide metformin.
1977 Lancet 22 Jan. 191/2 Metformin is replacing phenformin as the biguanide of choice in the treatment of obese maturity-onset diabetics.
1991 Longevity Jan. 46/3 Metformin and buformin are in the same class of drugs, but do not have serious side effects.
This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022).
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n.1961
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