单词 | metformin |
释义 | metforminn. Pharmacology. A biguanide derivative, C4H11N5, used, now chiefly as the hydrochloride, as an oral hypoglycaemic agent in the treatment of type 2 diabetes mellitus; 1,1-dimethylbiguanide. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for diabetes synthalin1927 protamine insulin1935 protamine zinc insulin1935 Ultralente1953 sulphonylurea1956 tolbutamide1956 phenformin1959 acetohexamide1961 metformin1961 tolazamide1963 1961 Lancet 24 June 1368/1 Effectiveness and better gastrointestinal tolerance have been claimed for dimethyldiguanide metformin. 1977 Lancet 22 Jan. 191/2 Metformin is replacing phenformin as the biguanide of choice in the treatment of obese maturity-onset diabetics. 1991 Longevity Jan. 46/3 Metformin and buformin are in the same class of drugs, but do not have serious side effects. This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022). < n.1961 |
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