mephenesinn.

Brit.

/mɛfəˈniːsɪn/, U.S.

/mɛfəˈnis(ə)n/

Origin: Formed within English, by derivation. Etymons: methyl n., phenyl n., cresol n., -in suffix¹.

Etymology: < me- (in methyl n.) + phen- (in phenyl n.) + -es- (in cresol n.) + -in suffix¹.

Pharmacology.

A colourless crystalline compound, CH₃·C₆H₄O·CH₂CH(OH)CH₂OH, which is used as a muscle relaxant in the treatment of spastic, hypertonic, and hyperkinetic conditions, and as a tranquillizer.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > tranquillizer > specific substances or preparations

nepenthes1580

nepenthe1595

Seconal1935

secobarbital1950

mephenesin1952

Largactil1953

Miltown1954

meprobamate1955

hydroxyzine1956

promazine1956

Sparine1956

prochlorperazine1957

Stelazine1958

trifluoperazine1958

Prolixin1959

chlordiazepoxide1960

Librium1960

diazepam1961

Valium1961

oxazepam1964

pimozide1968

lorazepam1969

temazepam1970

alprazolam1973

the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > antispasmodic or anticonvulsant > specific substances or preparations

Dilantin1938

phenytoin1942

Artane1948

Mysoline1949

mephenesin1952

troxidone1952

primidone1953

acetazolamide1954

orphenadrine1957

tetrabenazine1958

ethosuximide1960

methsuximide1965

clonazepam1970

valproic1972

valproate1974

1952 Brit. Pharmaceut. Codex 1949 Suppl. 40 Mephenesin consists of 3-(2-methylphenoxy)propane-1:2-diol.

1955 Sci. News Let. 16 July 40/3 In the great majority of 109 cases [of cerebral palsy] treated before dental surgery with mephenesin,..the drug produced feelings of well-being and relaxation, and nervousness diminished or disappeared.

1962 J. H. Burn Drugs, Med. & Man xii. 127 Another study was made by other workers to test the claim that the drug mephenesin exerts a specific effect on subjective anxiety and feeling of tension, and also on objective manifestations of this state.

1995 European Jrnl. Neurosci. 7 143 The involvement of lumbar interneurons was established by perfusing the lumbar enlargement with saline containing either a high concentration of divalent ions or mephenesin.

This entry has been updated (OED Third Edition, September 2001; most recently modified version published online March 2022).

单词	mephenesin
释义	mephenesinn. Brit. /mɛfəˈniːsɪn/, U.S. /mɛfəˈnis(ə)n/ Origin: Formed within English, by derivation. Etymons: methyl n., phenyl n., cresol n., -in suffix¹. Etymology: < me- (in methyl n.) + phen- (in phenyl n.) + -es- (in cresol n.) + -in suffix¹. Pharmacology. A colourless crystalline compound, CH₃·C₆H₄O·CH₂CH(OH)CH₂OH, which is used as a muscle relaxant in the treatment of spastic, hypertonic, and hyperkinetic conditions, and as a tranquillizer. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > tranquillizer > specific substances or preparations nepenthes1580 nepenthe1595 Seconal1935 secobarbital1950 mephenesin1952 Largactil1953 Miltown1954 meprobamate1955 hydroxyzine1956 promazine1956 Sparine1956 prochlorperazine1957 Stelazine1958 trifluoperazine1958 Prolixin1959 chlordiazepoxide1960 Librium1960 diazepam1961 Valium1961 oxazepam1964 pimozide1968 lorazepam1969 temazepam1970 alprazolam1973 the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > antispasmodic or anticonvulsant > specific substances or preparations Dilantin1938 phenytoin1942 Artane1948 Mysoline1949 mephenesin1952 troxidone1952 primidone1953 acetazolamide1954 orphenadrine1957 tetrabenazine1958 ethosuximide1960 methsuximide1965 clonazepam1970 valproic1972 valproate1974 1952 Brit. Pharmaceut. Codex 1949 Suppl. 40 Mephenesin consists of 3-(2-methylphenoxy)propane-1:2-diol. 1955 Sci. News Let. 16 July 40/3 In the great majority of 109 cases [of cerebral palsy] treated before dental surgery with mephenesin,..the drug produced feelings of well-being and relaxation, and nervousness diminished or disappeared. 1962 J. H. Burn Drugs, Med. & Man xii. 127 Another study was made by other workers to test the claim that the drug mephenesin exerts a specific effect on subjective anxiety and feeling of tension, and also on objective manifestations of this state. 1995 European Jrnl. Neurosci. 7 143 The involvement of lumbar interneurons was established by perfusing the lumbar enlargement with saline containing either a high concentration of divalent ions or mephenesin. This entry has been updated (OED Third Edition, September 2001; most recently modified version published online March 2022). < n.1952
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