metachromaticadj.

Brit.

/ˌmɛtəkrə(ʊ)ˈmatɪk/, U.S.

/ˈˌmɛdəˌkroʊˈmædɪk/

Origin: Formed within English, by derivation. Etymons: meta- prefix, chromatic adj.

Etymology: < meta- prefix + chromatic adj. In sense 2 after German metachromatisch (H. Hoyer 1890, in Arch. f. mikrosk. Anat. 36 314). Compare metachromatism n., metachrome n. and adj. and metachromic adj.²

†1. Chemistry. Of or relating to changes in colour produced by heating. Cf. metachrome n., metachromatism n. 1a. Obsolete. rare.

ΘΚΠ

the world > matter > colour > change of colour > [adjective] > relating to colour change

metachromatic1876

electrochromic1961

1876 Chem. News 11 Feb. 60/2 From a study of the two classes [of metachromes] the following metachromatic scale was arrived at:—White, colourless, violet, indigo, blue [etc.].

1876 W. Ackroyd in Chem. News 25 Aug. 75/2 A large series of spectroscopic observations were made of metachromatic solutions.

2. Histology and Biology. Of, relating to, exhibiting, or involving metachromasia.

ΘΚΠ

the world > life > biology > substance > staining quality of substance > [adjective]

basophil1890

neutrophil1890

neutrophilic1893

oxyphil1893

oxyphilous1893

basophilic1894

basophilous1894

metachromatic1894

polychromatophilic1897

polychromatophil1898

chromophil1899

chromophilic1899

chromophobic1899

orthochromatic1899

polychromatic1899

pycnomorphous1899

fuchsinophil1900

neutrophilous1900

carminophilous1901

chromatoid1901

oxyphilic1901

pyknotic1902

sudanophil1902

chromaffin1903

metachromic1908

chromophobe1909

phaeochrome1909

sudanophilic1909

trachychromatic1909

polychromasic1911

chromaffinic1913

osmiophilic1923

osmophile1923

Feulgen-negative1928

fuchsinophilic1931

heteropycnotic1934

osmophilic1936

isopycnotic1950

Feulgen-positive1954

1894 Philos. Trans. 1893 (Royal Soc.) B. 184 337 In the metachromatic staining reaction of thionin..one has..a reliable microscopic test for the presence of mucin.

1897 R. Muir & J. Ritchie Man. Bacteriol. i. 11 It is..very probable that the occurrence of metachromatic granules in a bacterium indicates the onset of degenerative changes.

1925 C. H. Browning Bacteriol. ii. 29 Sometimes with methylene-blue these beads stain of a different tint from the rest of the bacillus (metachromatic staining).

1945 J. R. Baker Cytol. Technique (ed. 2) vi. 166 The dyes exist in aqueous solution in two forms, the normal (blue) and metachromatic (red).

1968 New Eng. Jrnl. Med. 25 Jan. 210/2 In sections of the aorta..we found the metachromatic and cystic changes in the media that are characteristic of this condition.

1990 BioFactors 2 135/2 When stained with a metachromatic dye such as toluidine blue, the altered granules stain pink while the quiescent granules stain purple or dark blue.

3. Biology. Of or relating to metachromism in mammals (metachromism n. 2).

ΚΠ

1988 P. Hershkovitz in Proc. Acad. Nat. Sci. Philadelphia 140 240 The guide for and measure of evolutionary change of mammalian tegumentary coloration is described as metachromism. Three modes of metachromatic differentiation are described.

1990 Amer. Jrnl. Primatol. 21 1 Analyses of morphological differences between subspecies and among individual specimens relative to geographical and evolutionary distances (based on the metachromatic theory) were performed by using quadratic assignment procedures.

1995 Systematic Biol. 44 515 Coat colors for 16 chromogenetic regions of the tamarin coat were examined using the molecular phylogeny to test predictions of the metachromatic theory.

Compounds

metachromatic leukodystrophy n. Medicine any of a group of inherited diseases characterized by accumulation of the metachromatic lipid galactosyl sulphatide (cerebroside sulphate) in the central and peripheral nervous system and other organs, leading to severe cognitive and motor dysfunction and premature death.

ΚΠ

1960 Jrnl. Neuropathol. & Exper. Neurol. 19 334 A survey of the literature shows that there are apparently only 10 reported instances of pathologically verified cases of infantile metachromatic leukodystrophy.

1991 Lancet 21 Dec. 1603/1 We report here on our experience with this drug [sc. vigabatrin] in the symptomatic treatment of spasticity due to metabolic diseases with leukodystrophy in six children—three with metachromatic leukodystrophy [etc.].

Derivatives

metachroˈmatically adv.

ΘΚΠ

the world > life > biology > substance > staining quality of substance > [adverb]

metachromatically1908

1908 Anat. Rec. 2 106 Sections from such material stained in toluidene blue show the mucous secretion metachromatically stained, but no metachromatism is visible in the demilune cells.

1990 Jrnl. Zool. 220 314 The thin central and posterior parts of the disc..contain a substance which is coloured metachromatically with basophilic staining.

This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022).

单词	metachromatic
释义	metachromaticadj. Brit. /ˌmɛtəkrə(ʊ)ˈmatɪk/, U.S. /ˈˌmɛdəˌkroʊˈmædɪk/ Origin: Formed within English, by derivation. Etymons: meta- prefix, chromatic adj. Etymology: < meta- prefix + chromatic adj. In sense 2 after German metachromatisch (H. Hoyer 1890, in Arch. f. mikrosk. Anat. 36 314). Compare metachromatism n., metachrome n. and adj. and metachromic adj.² †1. Chemistry. Of or relating to changes in colour produced by heating. Cf. metachrome n., metachromatism n. 1a. Obsolete. rare. ΘΚΠ the world > matter > colour > change of colour > [adjective] > relating to colour change metachromatic1876 electrochromic1961 1876 Chem. News 11 Feb. 60/2 From a study of the two classes [of metachromes] the following metachromatic scale was arrived at:—White, colourless, violet, indigo, blue [etc.]. 1876 W. Ackroyd in Chem. News 25 Aug. 75/2 A large series of spectroscopic observations were made of metachromatic solutions. 2. Histology and Biology. Of, relating to, exhibiting, or involving metachromasia. ΘΚΠ the world > life > biology > substance > staining quality of substance > [adjective] basophil1890 neutrophil1890 neutrophilic1893 oxyphil1893 oxyphilous1893 basophilic1894 basophilous1894 metachromatic1894 polychromatophilic1897 polychromatophil1898 chromophil1899 chromophilic1899 chromophobic1899 orthochromatic1899 polychromatic1899 pycnomorphous1899 fuchsinophil1900 neutrophilous1900 carminophilous1901 chromatoid1901 oxyphilic1901 pyknotic1902 sudanophil1902 chromaffin1903 metachromic1908 chromophobe1909 phaeochrome1909 sudanophilic1909 trachychromatic1909 polychromasic1911 chromaffinic1913 osmiophilic1923 osmophile1923 Feulgen-negative1928 fuchsinophilic1931 heteropycnotic1934 osmophilic1936 isopycnotic1950 Feulgen-positive1954 1894 Philos. Trans. 1893 (Royal Soc.) B. 184 337 In the metachromatic staining reaction of thionin..one has..a reliable microscopic test for the presence of mucin. 1897 R. Muir & J. Ritchie Man. Bacteriol. i. 11 It is..very probable that the occurrence of metachromatic granules in a bacterium indicates the onset of degenerative changes. 1925 C. H. Browning Bacteriol. ii. 29 Sometimes with methylene-blue these beads stain of a different tint from the rest of the bacillus (metachromatic staining). 1945 J. R. Baker Cytol. Technique (ed. 2) vi. 166 The dyes exist in aqueous solution in two forms, the normal (blue) and metachromatic (red). 1968 New Eng. Jrnl. Med. 25 Jan. 210/2 In sections of the aorta..we found the metachromatic and cystic changes in the media that are characteristic of this condition. 1990 BioFactors 2 135/2 When stained with a metachromatic dye such as toluidine blue, the altered granules stain pink while the quiescent granules stain purple or dark blue. 3. Biology. Of or relating to metachromism in mammals (metachromism n. 2). ΚΠ 1988 P. Hershkovitz in Proc. Acad. Nat. Sci. Philadelphia 140 240 The guide for and measure of evolutionary change of mammalian tegumentary coloration is described as metachromism. Three modes of metachromatic differentiation are described. 1990 Amer. Jrnl. Primatol. 21 1 Analyses of morphological differences between subspecies and among individual specimens relative to geographical and evolutionary distances (based on the metachromatic theory) were performed by using quadratic assignment procedures. 1995 Systematic Biol. 44 515 Coat colors for 16 chromogenetic regions of the tamarin coat were examined using the molecular phylogeny to test predictions of the metachromatic theory. Compounds metachromatic leukodystrophy n. Medicine any of a group of inherited diseases characterized by accumulation of the metachromatic lipid galactosyl sulphatide (cerebroside sulphate) in the central and peripheral nervous system and other organs, leading to severe cognitive and motor dysfunction and premature death. ΚΠ 1960 Jrnl. Neuropathol. & Exper. Neurol. 19 334 A survey of the literature shows that there are apparently only 10 reported instances of pathologically verified cases of infantile metachromatic leukodystrophy. 1991 Lancet 21 Dec. 1603/1 We report here on our experience with this drug [sc. vigabatrin] in the symptomatic treatment of spasticity due to metabolic diseases with leukodystrophy in six children—three with metachromatic leukodystrophy [etc.]. Derivatives metachroˈmatically adv. ΘΚΠ the world > life > biology > substance > staining quality of substance > [adverb] metachromatically1908 1908 Anat. Rec. 2 106 Sections from such material stained in toluidene blue show the mucous secretion metachromatically stained, but no metachromatism is visible in the demilune cells. 1990 Jrnl. Zool. 220 314 The thin central and posterior parts of the disc..contain a substance which is coloured metachromatically with basophilic staining. This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022). < adj.1876
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