methylatorn.

Brit.

/ˈmɛθᵻleɪtə/, U.S.

/ˈmɛθəˌleɪdər/

Origin: Formed within English, by derivation. Etymons: methylate v., -or suffix.

Etymology: < methylate v. + -or suffix.

1. A person or company engaged in the production of methylated spirits.

ΚΠ

1880 Act 43 & 44 Vict. c. 24 §126 A retailer..must not receive methylated spirits except from an authorised methylator.

1910 Chambers's Jrnl. Feb. 103/2 The methylator had not the slightest interest in putting in one drop more naphtha than the Excise officials compelled him to utilise.

1922 G. W. Monier-Williams Power Alcohol vii. 198 The conversion of the alcohol into power methylated spirits may be carried out only by an authorised methylator.

1987 Methylated Spirits Regulations §2 ‘Methylator’ means an authorised methylator under section 75(1) of the Alcoholic Liquor Duties Act 1979.

2. Chemistry and Biology. A chemical compound or drug that is a methylating agent or methyl group donor; an organism, tumour, or cell that is capable of carrying out a specific type of metabolic methylation reaction.In quot. 1961: (perhaps) an apparatus for carrying out methylation.

ΚΠ

1961 Chem. Engin. Thesaurus 125/2 Reactors...Methylators.

1982 Drug–Nutrient Interactions 1 303 Hepatic betaine, the secondary methylator of homocysteine in the liver, also increased in the controls during the experimental period.

1984 Federation Proc. (Federation Amer. Soc. Exper. Biol.) 43 2303 Genetically determined methylator status may be one factor responsible for variations in drug metabolism in humans.

1997 Jrnl. Biol. Chem. 272 24730/1 The resistance of repair-defective cells to DNA methylators and cisplatin raises questions concerning appropriate chemotherapeutic regimens for treatment of MIN⁺ tumors.

1999 Proc. National Acad. Sci. U.S.A. 96 8681 Methylation of the cancer-specific [DNA] clones was found exclusively in a subset of colorectal cancers, which appear to display a CpG island methylator phenotype.

2000 Appl. & Environmental Microbiol. 66 1479 Analysis..suggests that Desulfobacter-like organisms are important mercury methylators in the sediments, especially in the Lower Arm of Clear Lake.

This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022).

单词	methylator
释义	methylatorn. Brit. /ˈmɛθᵻleɪtə/, U.S. /ˈmɛθəˌleɪdər/ Origin: Formed within English, by derivation. Etymons: methylate v., -or suffix. Etymology: < methylate v. + -or suffix. 1. A person or company engaged in the production of methylated spirits. ΚΠ 1880 Act 43 & 44 Vict. c. 24 §126 A retailer..must not receive methylated spirits except from an authorised methylator. 1910 Chambers's Jrnl. Feb. 103/2 The methylator had not the slightest interest in putting in one drop more naphtha than the Excise officials compelled him to utilise. 1922 G. W. Monier-Williams Power Alcohol vii. 198 The conversion of the alcohol into power methylated spirits may be carried out only by an authorised methylator. 1987 Methylated Spirits Regulations §2 ‘Methylator’ means an authorised methylator under section 75(1) of the Alcoholic Liquor Duties Act 1979. 2. Chemistry and Biology. A chemical compound or drug that is a methylating agent or methyl group donor; an organism, tumour, or cell that is capable of carrying out a specific type of metabolic methylation reaction.In quot. 1961: (perhaps) an apparatus for carrying out methylation. ΚΠ 1961 Chem. Engin. Thesaurus 125/2 Reactors...Methylators. 1982 Drug–Nutrient Interactions 1 303 Hepatic betaine, the secondary methylator of homocysteine in the liver, also increased in the controls during the experimental period. 1984 Federation Proc. (Federation Amer. Soc. Exper. Biol.) 43 2303 Genetically determined methylator status may be one factor responsible for variations in drug metabolism in humans. 1997 Jrnl. Biol. Chem. 272 24730/1 The resistance of repair-defective cells to DNA methylators and cisplatin raises questions concerning appropriate chemotherapeutic regimens for treatment of MIN⁺ tumors. 1999 Proc. National Acad. Sci. U.S.A. 96 8681 Methylation of the cancer-specific [DNA] clones was found exclusively in a subset of colorectal cancers, which appear to display a CpG island methylator phenotype. 2000 Appl. & Environmental Microbiol. 66 1479 Analysis..suggests that Desulfobacter-like organisms are important mercury methylators in the sediments, especially in the Lower Arm of Clear Lake. This entry has been updated (OED Third Edition, December 2001; most recently modified version published online March 2022). < n.1880
随便看	antipathist antipathists antipathite antipathize antipathizing antipathous antipathy antipatriarchal antipatriotic antipaul antipedagogic antipelagian antipelargy antipentagonist antipeople antiperiodic antiperiodics antiperistalses antiperistalsis antiperistaltic antiperistases antiperistasis antiperistatic antiperistatical antiperistatically