methylmalonyladj.

Brit.

/ˌmiːθʌɪlˈmalənɪl/, U.S.

/ˌmɛθəlˈmæləˌnɪl/

Origin: Formed within English, by derivation. Etymons: methylmalonic adj., -yl suffix.

Etymology: < methylmalon- (in methylmalonic adj.) + -yl suffix.

Chemistry and Biochemistry.

The acyl group derived from methylmalonic acid; esp. in methylmalonyl coenzyme A, methylmalonyl CoA, the coenzyme A derivative of methylmalonic acid, which is an intermediate in the metabolism of certain amino acids and fatty acids.

ΚΠ

1955 Nature 29 Oct. 826/1 The product of carboxylation of propionyl coenzyme A might be methylmalonyl coenzyme A.

1984 Antimicrobial Agents & Chemotherapy 25 173 Streptomyces erythreus produces erythromycin, presumably from methylmalonyl-coenzyme A.

1993 New Scientist 11 Sept. 41/2 If there is no glycoprotein, the vitamin cannot be absorbed, and the deficiency results in a build-up of a substance called methylmalonyl coenzyme A.

1998 Proc. National Acad. Sci. U.S.A. 95 7305/2 A methylmalonyl-specific AT [= acyltransferase].

This is a new entry (OED Third Edition, December 2001; most recently modified version published online March 2022).

单词	methylmalonyl
释义	methylmalonyladj. Brit. /ˌmiːθʌɪlˈmalənɪl/, U.S. /ˌmɛθəlˈmæləˌnɪl/ Origin: Formed within English, by derivation. Etymons: methylmalonic adj., -yl suffix. Etymology: < methylmalon- (in methylmalonic adj.) + -yl suffix. Chemistry and Biochemistry. The acyl group derived from methylmalonic acid; esp. in methylmalonyl coenzyme A, methylmalonyl CoA, the coenzyme A derivative of methylmalonic acid, which is an intermediate in the metabolism of certain amino acids and fatty acids. ΚΠ 1955 Nature 29 Oct. 826/1 The product of carboxylation of propionyl coenzyme A might be methylmalonyl coenzyme A. 1984 Antimicrobial Agents & Chemotherapy 25 173 Streptomyces erythreus produces erythromycin, presumably from methylmalonyl-coenzyme A. 1993 New Scientist 11 Sept. 41/2 If there is no glycoprotein, the vitamin cannot be absorbed, and the deficiency results in a build-up of a substance called methylmalonyl coenzyme A. 1998 Proc. National Acad. Sci. U.S.A. 95 7305/2 A methylmalonyl-specific AT [= acyltransferase]. This is a new entry (OED Third Edition, December 2001; most recently modified version published online March 2022). < adj.1955
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