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单词 mispairing
释义

mispairingn.

Brit. /ˌmɪsˈpɛːrɪŋ/, U.S. /ˌmɪsˈpɛrɪŋ/
Origin: Formed within English, by derivation. Etymons: mis- prefix1, pairing n.2
Etymology: < mis- prefix1 + pairing n.2 Compare earlier mispaired adj.
Incorrect or inappropriate pairing; (Molecular Biology) incorrect or inaccurate base pairing (cf. mispair v. 1). Also: an instance of such pairing.
ΚΠ
1900 Amer. Jrnl. Sociol. 5 707 An appliance for preventing the mispairing of overshoes.
1964 Shakespeare Q. 15 119 Both the mispairings and the proper pairings of love, on this single night, we can witness as produced by fairy influence.
1966 Science 16 Sept. 1403/1 It has been proposed that the mutagenic effects in DNA may result from the mispairing of 7-methylguanine with thymine during replication.
1976 Nature 23 Sept. 285/1 The bi-helical complementary base-paired structure of DNA implies mispairing events as the principal means for generating substitution mutations.
1985 Science 20 Sept. 1278/2 If the mispairing is resolved by replication, there is no mechanism for determining which daughter DNA is correct.
1995 Accounting Today (Nexis) 22 May 18 These mispairings are a result of the firm's partners not fully understanding what role they want their marketing director to play.
2000 New Scientist 28 Oct. 36/1 Some common AIDS drugs such as AZT are also base analogues, but instead of causing mispairings, they simply shut down viral replication altogether.
This is a new entry (OED Third Edition, June 2002; most recently modified version published online March 2022).
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n.1900
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