单词 | misincorporate |
释义 | misincorporatev. Molecular Biology. transitive. To bring about the misincorporation of (a nucleotide or amino acid). Also intransitive. ΚΠ 1975 Nucleic Acids Res. 2 1513 GTP is found to be misincorporated into both copolymers at a frequency of 1 per 1000–2000 nucleotides polymerized. 1986 Proc. National Acad. Sci. U.S.A. 83 28/1 On replication it could behave as deoxycytidine and misincorporate dGTP. 1990 EMBO Jrnl. 9 4186/1 Slippage mutants may even predominate; i.e. the polymerase could slip more frequently than misincorporate. 1998 Proc. National Acad. Sci. U.S.A. 95 11146/2 Ribosomes are known to misincorporate amino acids at frequencies as high as 10-4 to 10-3 per codon. This is a new entry (OED Third Edition, June 2002; most recently modified version published online March 2022). < v.1975 |
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