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单词 misincorporate
释义

misincorporatev.

Brit. /ˌmɪs(ᵻ)nˈkɔːpəreɪt/, /ˌmɪsɪŋˈkɔːpəreɪt/, U.S. /ˌmɪsᵻnˈkɔrpəˌreɪt/, /ˌmɪsɪŋˈkɔrpəˌreɪt/
Origin: Formed within English, by derivation. Etymons: mis- prefix1, incorporate v.
Etymology: < mis- prefix1 + incorporate v., after misincorporated adj., misincorporation n.
Molecular Biology.
transitive. To bring about the misincorporation of (a nucleotide or amino acid). Also intransitive.
ΚΠ
1975 Nucleic Acids Res. 2 1513 GTP is found to be misincorporated into both copolymers at a frequency of 1 per 1000–2000 nucleotides polymerized.
1986 Proc. National Acad. Sci. U.S.A. 83 28/1 On replication it could behave as deoxycytidine and misincorporate dGTP.
1990 EMBO Jrnl. 9 4186/1 Slippage mutants may even predominate; i.e. the polymerase could slip more frequently than misincorporate.
1998 Proc. National Acad. Sci. U.S.A. 95 11146/2 Ribosomes are known to misincorporate amino acids at frequencies as high as 10-4 to 10-3 per codon.
This is a new entry (OED Third Edition, June 2002; most recently modified version published online March 2022).
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v.1975
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