单词 | moloney |
释义 | Moloneyn. Virology. attributive. Designating either of two closely-related retroviruses that are oncogenic in mice, one of which (in full Moloney leukaemia virus, Moloney murine leukaemia virus) causes lymphomas and leukaemia, and the other of which (in full Moloney murine sarcoma virus, Moloney sarcoma virus) causes rhabdomyosarcomas. ΚΠ 1963 Science 10 May 688/2 (advt.) Potent antisera (rabbit) for..Moloney leukemia virus. 1963 Science 5 July 40/3 An interval of greater than 2 weeks between inoculation of Moloney virus and challenge with Friend virus was necessary in order to establish resistance to the latter. 1966 Proc. National Acad. Sci. U.S.A. 55 780 (title) Production of altered cell foci in tissue culture by defective Moloney sarcoma virus particles. 1969 Proc. National Acad. Sci. U.S.A. 62 1046 The majority of NIH Swiss mice inoculated with Moloney or Friend pseudotypes of Moloney murine sarcoma virus failed to develop tumors. 1977 Ann. Internal Med. 86 326/2 This hypothesis is supported..by the observation of an increased frequency of Moloney-virus induced tumors in Plasmodium-infected adult Balb-C mice. 1990 EMBO Jrnl. 9 4155/1 To examine the restriction of HIV growth in murine cells, we infected NIH 3T3 cells with HIV pseudotyped by Moloney murine leukaemia virus. 1992 C. A. Kozak & S. Ruscetti in J. A. Levy Retroviridae I. vii. 436 Moloney murine sarcoma virus (M-MSV) was isolated by injecting a high dose of Moloney MuLV into BALB/c mice (Moloney, 1966)... M-MSV is a recombinant between Moloney MuLV and the mouse proto-oncogene mos. 1994 New Scientist 12 Feb. 4/3 Gallimore's team has spliced the oncogene into the genetic material of two other viruses—type five human adenovirus.., and a retrovirus called the mouse Moloney virus, which causes leukaemia in mice. This is a new entry (OED Third Edition, September 2002; most recently modified version published online March 2022). < n.1963 |
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