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单词 monensin
释义

monensinn.

Brit. /məˈnɛnsɪn/, U.S. /məˈnɛnsɪn/
Origin: A borrowing from Latin, combined with an English element. Etymons: Latin cinnamonensis , -in suffix1.
Etymology: < monens- (in scientific Latin cinnamonensis, specific epithet < classical Latin cinnamon cinnamon n. + -ēnsis : see -ese suffix) + -in suffix1.The bacterium is named after the colour of its cultures, which resembles cinnamon.
Cell Biology and Veterinary Medicine.
An open-chain polyether produced by the bacterium Streptomyces cinnamonensis, which acts as an ionophore for monovalent cations and inhibits protein transport and various other cellular functions, and which is used in veterinary medicine as an antibiotic, chiefly for growth promotion in cattle.
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the world > life > biology > organism > micro-organism > bacterium > [noun] > substances produced by
colicin1946
virginiamycin1961
monensin1967
1967 Jrnl. Amer. Chem. Soc. 89 5738/2 (note) The name monensic acid has been changed to monensin upon the recommendation of the USAN Council.
1968 M. E. Haney & M. M. Hoehn in Antimicrobial Agents & Chemotherapy 1967 349 Monensin (previously referred to as monensic acid) is the major factor in a group of closely related, biologically active compounds produced by a new strain of Streptomyces cinnamonensis.
1976 Science 6 Feb. 453/3 Feedlot cattle will normally eat only enough to satisfy their energy needs, Muller says, so monensin does not increase their average daily weight gain.
1988 Exper. Cell Res. 174 472 The proton ionophore monensin prevents acidification of endosomes and reversibly inhibits this acid-dependent dissociation of ligand from receptor.
1994 Jrnl. Cell Biol. 124 893 In wild-type cells, proteolytic processing is blocked in the presence of monensin.
2001 Antimicrobial Agents & Chemotherapy 45 1374 Acquired resistance against flavomycin and monensin, two antibiotics used solely for growth promotion, was not detected.
This is a new entry (OED Third Edition, September 2002; most recently modified version published online March 2022).
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n.1967
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