monocompoundn.
/ˈmɒnə(ʊ)ˌkɒmpaʊnd/, U.S. /ˈmɑnəˌkɑmpaʊn(d)/ 1. Chemistry. In inorganic chemistry: a compound, esp. a binary compound, whose molecule contains one atom of a specified element. In organic chemistry: a derivative whose molecule contains only a single substituted group or radical.
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1865 H. Watts Dict. Chem. III. 1047 Mono-compounds. This term is applied to compounds containing 1 at. of the element specified.
1872 Proc. Royal Soc. 1871–2 20 231 Dimethylphosphinic acid is less suitable for analysis than the mono-compound.
1942 Condensed Chem. Dict. (ed. 3) 444/2 Mono Compounds, see under specific compounds; e.g., Monoacetin. See Acetin.
1980 Internat. Jrnl. Quantum Chem. 17 1167 (title) Projected surface energy bands, Shockley surface states, and bonding in transition-metal monocompounds with rock-salt structure: example of NbC.
1985 Physics & Chem. Materials Treatm. 19 76/1 Investigations were conducted into the creep of uranium monocompounds UC, UN, UP, US in compressive loading in the temperature range 1470–2270K.
1989 Arch. Pharmacal Res. 12 233 Triacyl mannitols of capric and myristic acid have better emulsifying property than the corresponding di and monocompounds.
2. Pharmacology. A pharmaceutical drug used alone, as in monotherapy.
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1989 Clin. Therapeutics 11 341 As a monocompound it [sc. guaimesal] relieves the physician and the patient of the trouble and risk associated with alternative fixed-combination or multiple-drug treatments.
1997 Jrnl. Hypertension 15 Suppl. II. S51 The profile of adverse drug reactions of a fixed-dose combination of verapamil and trandolapril consists [sic] the typical side effects of the monocompounds.
This entry has been updated (OED Third Edition, December 2002; most recently modified version published online March 2022).
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