单词 | mptp |
释义 | > as lemmasMPTP MPTP n. Pharmacology 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, C12H15N, a piperidine derivative which causes irreversible parkinsonism in monkeys and humans. ΚΠ 1983 Science 25 Feb. 979 Four persons developed marked parkinsonism after using an illicit drug intravenously. Analysis of the substance injected by two of these patients revealed primarily 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP). 1991 New Scientist 17 Aug. 24/1 Among other things, it appears that the body metabolises MPTP, generating a chemical similar to dopamine which is then taken up selectively by dopaminergic neurons. < as lemmas |
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