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单词 mptp
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MPTP
MPTP n. Pharmacology 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, C12H15N, a piperidine derivative which causes irreversible parkinsonism in monkeys and humans.
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1983 Science 25 Feb. 979 Four persons developed marked parkinsonism after using an illicit drug intravenously. Analysis of the substance injected by two of these patients revealed primarily 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP).
1991 New Scientist 17 Aug. 24/1 Among other things, it appears that the body metabolises MPTP, generating a chemical similar to dopamine which is then taken up selectively by dopaminergic neurons.
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