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单词 muscarine
释义

muscarinen.

Brit. /ˈmʌskəriːn/, /ˈmʌskərɪn/, U.S. /ˈməskərən/, /ˈməskəˌrin/
Forms: 1800s–1900s muscarin, 1800s– muscarine.
Origin: A borrowing from German. Etymon: German Muscarin.
Etymology: < German Muscarin (O. Schmiedeberg and R. Koppe Das Muscarin (1869) 2) < scientific Latin muscarius , use as specific epithet (see quot. 1869) of classical Latin muscārius (see muscarious adj.) + German -in -ine suffix5.
Chemistry and Physiology.
A quaternary ammonium base, C9H21NO3, found in the fly agaric ( Amanita muscaria) and certain other fungi, which is a poisonous alkaloid which mimicks the neurotransmitter acetylcholine causing nausea and vomiting, bradycardia, and copious secretion by the mucous and sweat glands.
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the world > physical sensation > use of drugs and poison > poison > [noun] > from fungus or bacterium > from specific fungus
muscarine1869
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the world > matter > chemistry > organic chemistry > poisons > [noun] > others
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1869 Nature 2 Dec. 144/1 Schmiedeberg and Koppe have published an account of the pharmacy and physiological action of muscarin, the active constituent of agaricus muscarius.
1878 tr. H. W. von Ziemssen et al. Cycl. Pract. Med. XVII. 936 Muscarine contracts the pupils.
1910 Practitioner June 824 Putrefactive organisms split up proteins into..ptomaines—neurin, cholin, muscarin, cadaverin, [etc.].
1940 H. A. McGuigan Appl. Pharmacol. 576 The action of pilocarpine and muscarine..seems to be on the parasympathetic nerve endings and not directly on the gland cell.
1951 J. Steinbeck & E. F. Ricketts Log from ‘Sea of Cortez’ xii. 124 Muscarine, the active poisonous principle of Amanita muscaria and other fungi.
1961 Q. Rev. Chem. Soc. 15 154 The story of muscarine revolves round the presentation of three formulae, two erroneous ones C5H14O2N+ and C8H18O2N+, and the correct one C9H20O2N+.
1989 E. Lawrence Guide Mod. Biol. ix. 259 Another group of ACh receptors..are blocked by muscarine and related alkaloids.
This entry has been updated (OED Third Edition, March 2003; most recently modified version published online March 2022).
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n.1869
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