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单词 muscarinic
释义

muscarinicadj.

Brit. /mʌskəˈrɪnɪk/, U.S. /ˌməskəˈrɪnɪk/
Origin: Formed within English, by derivation. Etymons: muscarine n., -ic suffix.
Etymology: < muscarine n. + -ic suffix.
Physiology.
Resembling muscarine or its physiological action, esp. on certain receptors in the nervous system; (of a receptor) capable of responding to muscarine.
ΘΚΠ
the world > physical sensation > use of drugs and poison > poison > [adjective] > resembling specific poison
aconital1652
muscarinic1941
the world > matter > chemistry > organic chemistry > poisons > [adjective]
muscarinic1941
nicotinic1941
the world > life > biology > substance > process stimulators or inhibitors > antibody > [adjective] > capable of responding to poisons, etc.
muscarinic1961
1941 L. S. Goodman & A. Z. Gilman Pharmacol. Basis Therapeutics xix. 339 The nicotinic and muscarinic actions of acetylcholine can be strikingly demonstrated on the intestinal tract of..the tench.
1961 Nature 25 Feb. 673/1 Observed differences in the muscarinic activities of the above isomers is [sic] therefore explicable in terms of differences in their fit at the muscarinic receptors.
1974 Canad. Jrnl. Physiol. & Pharmacol. 52 332/2 An alternative explanation..is based on the concepts that there exist separate binding subsites on the muscarinic receptor to accommodate the polar and nonpolar side chains of muscarinic agonists [etc.].
1990 Brain 113 1294 Increased doses of pyridostigmine produced muscarinic side effects.
This entry has been updated (OED Third Edition, March 2003; most recently modified version published online March 2022).
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adj.1941
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