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单词 myelodysplastic
释义

myelodysplasticadj.

Brit. /ˌmʌɪələ(ʊ)dɪsˈplastɪk/, U.S. /ˈˌmaɪəloʊˌdɪsˈplæstɪk/
Origin: Formed within English, by compounding. Etymons: myelo- comb. form, dysplastic adj.
Etymology: < myelo- comb. form + dysplastic adj., after myelodysplasia n.
Pathology.
1. Affected by or relating to dysplasia of the spinal cord (myelodysplasia n. 1).
ΚΠ
1963 Jrnl. Amer. Med. Assoc. 8 June 765/1 The ultimate goal of orthopedic management of myelodysplastic children should be to achieve independent ambulation whenever feasible.
1977 Jrnl. Urol. 117 501 Alternative methods to supravesical urinary diversion in myelodysplastic children..are now available.
1985 Jrnl. Neurosurg. 62 367 Seventeen myelodysplastic patients with progressive extremity spasticity and scoliosis underwent radiological evaluation and surgical treatment.
1998 Jrnl. Pediatric Surg. 33 1108 Latex sensitization is a well-documented occurrence in children with myelodysplastic and urologic anomalies.
2. Characterized by, relating to, or affected by dysplasia of bone marrow and blood cells (myelodysplasia n. 2); esp. in myelodysplastic syndrome.
ΚΠ
1966 J. D. Rowley et al. in Blood 27 782 These preleukemic or, more precisely, potentially leukemic syndromes may be classified into the aplastic, myelodysplastic, and myeloproliferative disorders.
1983 Blood 61 449 Quantitative abnormalities in lymphocytic subpopulations from myelodysplastic patients also were observed.
1987 Nature 4 June 430/1 Patients with a myelodysplastic syndrome (MDS) which has a risk of leukaemic change exhibit a variable clinical course.
1996 D. J. Weatherall et al. Oxf. Textbk. Med. (ed. 3) III. xxii. 3425/2 Two major types of myelodysplastic syndrome can be recognized, both carrying an increased risk of tranformation to acute myeloid leukaemia.
2002 Proc. National Acad. Sci. U.S.A. 99 6136 Recurring interstitial loss of all or part of the long arm of chromosome 5, del(5q), is a hallmark of myelodysplastic syndrome and acute myeloid leukemia.
This is a new entry (OED Third Edition, June 2003; most recently modified version published online March 2022).
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adj.1963
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