naproxenn.

Brit.

/naˈprɒksɛn/, U.S.

/nəˈprɑks(ə)n/

Origin: Formed within English, by compounding. Etymons: naphthyl n., propionic adj., oxy- comb. form², -ene comb. form.

Etymology: < na- (in naphthyl n.) + pr- (in propionic adj.) + ox- (in oxy- comb. form²) + -en (compare -ene comb. form).

Pharmacology.

A propionic acid derivative that is a non-steroidal anti-inflammatory drug; d-2-(6-methoxy-2-naphthyl)propionic acid, CH₃·C₁₀H₅·CH(CH₃)COOH.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics

Hoffmann's anodyne1747

acetylsalicylic acid1873

acetophenetidin1888

exalgin1889

pyramidon1898

aspirin1899

phenazone1899

Veganin1926

Trilene1935

Demerol1940

pethidine1942

Tridione1944

amidone1946

meperidine1947

methadone1947

Physeptone1947

Butazolidin1951

phenylbutazone1952

opioid1955

Panadol1955

propoxyphene1955

Tylenol1956

acetaminophen1957

paracetamol1957

Distalgesic1958

oxycodone1958

Sernyl1958

morphinomimetic1959

phencyclidine1959

levorphanol1960

mefenamic acid1962

pentazocine1964

Talwin1965

ibuprofen1967

nalbuphine1969

naproxen1971

phy1971

Nurofen1982

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for arthritis, rheumatism, or gout > others

Portland powder1763

helmitol1903

probenecid1950

indomethacin1963

allopurinol1964

ibuprofen1967

naproxen1971

sulindac1975

1971 Jrnl. Pharmacol. & Exper. Therapeutics 174 121/1 Naproxen appears to act directly at inflamed tissue sites, probably in the same manner as other nonsteroidal agents like indomethacin and mefenamic acid act.

1980 Nature 20 Mar. 272/2 Pretreatment of rats with aspirin, indomethacin, naproxen and flurbiprofen always led to a potent inhibition of prostacyclin production ex vivo.

1988 Jrnl. Internat. Med. Res. 16 158/1 Recently, an oral instant suspension formulation of naproxen has become available.

1994 Coloradoan (Fort Collins) 29 Jan. d8/5 Syntex Corp..took its best-selling anti-arthritis drug naproxen..over-the-counter earlier this month.

2002 N.Y. Times 22 Jan. (Washington Final ed.) d7/1 In addition to ibuprofen and naproxen, the class [of Nsaids] includes aspirin and the prescription drugs known as cox-2 inhibitors.

This entry has been updated (OED Third Edition, June 2003; most recently modified version published online March 2022).

单词	naproxen
释义	naproxenn. Brit. /naˈprɒksɛn/, U.S. /nəˈprɑks(ə)n/ Origin: Formed within English, by compounding. Etymons: naphthyl n., propionic adj., oxy- comb. form², -ene comb. form. Etymology: < na- (in naphthyl n.) + pr- (in propionic adj.) + ox- (in oxy- comb. form²) + -en (compare -ene comb. form). Pharmacology. A propionic acid derivative that is a non-steroidal anti-inflammatory drug; d-2-(6-methoxy-2-naphthyl)propionic acid, CH₃·C₁₀H₅·CH(CH₃)COOH. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics Hoffmann's anodyne1747 acetylsalicylic acid1873 acetophenetidin1888 exalgin1889 pyramidon1898 aspirin1899 phenazone1899 Veganin1926 Trilene1935 Demerol1940 pethidine1942 Tridione1944 amidone1946 meperidine1947 methadone1947 Physeptone1947 Butazolidin1951 phenylbutazone1952 opioid1955 Panadol1955 propoxyphene1955 Tylenol1956 acetaminophen1957 paracetamol1957 Distalgesic1958 oxycodone1958 Sernyl1958 morphinomimetic1959 phencyclidine1959 levorphanol1960 mefenamic acid1962 pentazocine1964 Talwin1965 ibuprofen1967 nalbuphine1969 naproxen1971 phy1971 Nurofen1982 the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for arthritis, rheumatism, or gout > others Portland powder1763 helmitol1903 probenecid1950 indomethacin1963 allopurinol1964 ibuprofen1967 naproxen1971 sulindac1975 1971 Jrnl. Pharmacol. & Exper. Therapeutics 174 121/1 Naproxen appears to act directly at inflamed tissue sites, probably in the same manner as other nonsteroidal agents like indomethacin and mefenamic acid act. 1980 Nature 20 Mar. 272/2 Pretreatment of rats with aspirin, indomethacin, naproxen and flurbiprofen always led to a potent inhibition of prostacyclin production ex vivo. 1988 Jrnl. Internat. Med. Res. 16 158/1 Recently, an oral instant suspension formulation of naproxen has become available. 1994 Coloradoan (Fort Collins) 29 Jan. d8/5 Syntex Corp..took its best-selling anti-arthritis drug naproxen..over-the-counter earlier this month. 2002 N.Y. Times 22 Jan. (Washington Final ed.) d7/1 In addition to ibuprofen and naproxen, the class [of Nsaids] includes aspirin and the prescription drugs known as cox-2 inhibitors. This entry has been updated (OED Third Edition, June 2003; most recently modified version published online March 2022). < n.1971
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