nemalineadj.

Brit.

/ˈnɛməlʌɪn/,

/ˈniːməlʌɪn/, U.S.

/ˈniməˌlaɪn/,

/ˈnɛməˌlaɪn/,

/ˈniməl(ə)n/,

/ˈnɛməl(ə)n/

Origin: A borrowing from Greek, combined with an English element. Etymons: Greek νῆμα , -ine suffix¹.

Etymology: < ancient Greek νῆμα thread (see nemato- comb. form) + -ine suffix¹, with insertion of -l- perhaps after nemalite n.

Chiefly Medicine.

†1. Mineralogy. Thread-like, fibrous. Obsolete. rare.

ΘΚΠ

the world > the earth > minerals > types of mineral > oxides and hydroxides > [adjective] > brucite

nemaline1835

1835 C. U. Shepard Treat. Mineral. II. 78 Nemalite, Nemaline Atelene Picrosmine.

2. Medicine. Designating a group of congenital myopathies characterized by the accumulation of rod-like bodies in muscle fibres; (also) designating the rod-like bodies present in such myopathies and in certain other muscle diseases.

ΘΚΠ

the world > health and disease > ill health > a disease > congenital or hereditary syndromes > [adjective]

Meige1950

nemaline1963

Down1964

1963 G. M. Shy et al. in Brain 86 793 (title) Nemaline myopathy, a new congenital myopathy.

1963 G. M. Shy et al. in Brain 86 807 Since these structures could represent rods or coils of thread like fibrous structures, it was deemed appropriate to name this disorder ‘nemaline myopathy’.

1967 Brain 90 823 The nemaline bodies have been considered to represent excessive accumulation of tropomyosin B.

1992 Jrnl. Amer. Vet. Med. Assoc. 201 1209 Ultrastructural examination revealed nemaline rods and swollen mitochondria in disrupted myofibers.

2002 Neuromuscular Disorders 12 680 We report mutational analysis of the last 42 exons of the nebulin gene (NEB) in 77 patients with various forms of nemaline myopathy.

This entry has been updated (OED Third Edition, September 2003; most recently modified version published online March 2022).

单词	nemaline
释义	nemalineadj. Brit. /ˈnɛməlʌɪn/, /ˈniːməlʌɪn/, U.S. /ˈniməˌlaɪn/, /ˈnɛməˌlaɪn/, /ˈniməl(ə)n/, /ˈnɛməl(ə)n/ Origin: A borrowing from Greek, combined with an English element. Etymons: Greek νῆμα , -ine suffix¹. Etymology: < ancient Greek νῆμα thread (see nemato- comb. form) + -ine suffix¹, with insertion of -l- perhaps after nemalite n. Chiefly Medicine. †1. Mineralogy. Thread-like, fibrous. Obsolete. rare. ΘΚΠ the world > the earth > minerals > types of mineral > oxides and hydroxides > [adjective] > brucite nemaline1835 1835 C. U. Shepard Treat. Mineral. II. 78 Nemalite, Nemaline Atelene Picrosmine. 2. Medicine. Designating a group of congenital myopathies characterized by the accumulation of rod-like bodies in muscle fibres; (also) designating the rod-like bodies present in such myopathies and in certain other muscle diseases. ΘΚΠ the world > health and disease > ill health > a disease > congenital or hereditary syndromes > [adjective] Meige1950 nemaline1963 Down1964 1963 G. M. Shy et al. in Brain 86 793 (title) Nemaline myopathy, a new congenital myopathy. 1963 G. M. Shy et al. in Brain 86 807 Since these structures could represent rods or coils of thread like fibrous structures, it was deemed appropriate to name this disorder ‘nemaline myopathy’. 1967 Brain 90 823 The nemaline bodies have been considered to represent excessive accumulation of tropomyosin B. 1992 Jrnl. Amer. Vet. Med. Assoc. 201 1209 Ultrastructural examination revealed nemaline rods and swollen mitochondria in disrupted myofibers. 2002 Neuromuscular Disorders 12 680 We report mutational analysis of the last 42 exons of the nebulin gene (NEB) in 77 patients with various forms of nemaline myopathy. This entry has been updated (OED Third Edition, September 2003; most recently modified version published online March 2022). < adj.1835
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