neurofibrillaryadj.

1902 Jrnl. Nerv. & Mental Dis. 29 435 The author concludes..that a neuro-fibrillary structure of nerve cells and their processes..is abundantly proven.

1949 B. W. Lichtenstein Textbk. Neuropathol. iv. 46 Neurofibrillary abnormalities occur in a variety of disease states. The normal configuration of the neurofibrillar apparatus is well seen in preparations impregnated with silver according to Bielschowsky's method.

1958 Brit. Jrnl. Philos. Sci. 9 262 Reference is being made to one of these neuro-physiological theories..which endeavours to describe conscious and unconscious thinking in terms of biological processes taking place in the various neuro-fibrillary systems.

1987 Proc. National Acad. Sci. U.S.A. 1 May 3036/1 The identification of specific posttranslational modifications on neurofibrillary structures in Alzheimer-affected brain tissue may provide important information toward an understanding of the formation of these abnormal and insoluble fibrils.

2000 Jrnl. Cell Sci. 113 1373 These results suggest that tau filament formation may be responsible for many key cytopathological features of neurofibrillary degeneration.

1963 Jrnl. Neuropathol. & Exper. Neurol. 22 629 The neurofibrillary tangle of Alzheimer is one of the most distinctive cytopathologic changes that occur in the central nervous system.

1988 New Scientist 12 Nov. 46/1 Neurofibrillary tangles are bundles of twisted filaments that accumulate within brain cells.

1996 O. Sacks Island of Colour-blind ii. 189 The monkeys developed no clinical symptoms in the four years of the trial, but autopsies showed many neurofibrillary tangles, as well as degenerative changes in the motor neurons.