nifedipinen.

Brit.

/nʌɪˈfɛdᵻpiːn/, U.S.

/ˌnaɪˈfɛdəˌpin/

Origin: Formed within English, by compounding. Etymons: nitro- comb. form, phenyl n., -dipine comb. form.

Etymology: < ni- (in nitro- comb. form) + fe- (representing phenyl n.) + -dipine comb. form (contraction of dihydropyridine n.).

Pharmacology.

A dihydropyridine calcium channel blocker, used chiefly for the treatment of hypertension, angina pectoris, and Raynaud's phenomenon; 1,4-dihydro-2,6-dimethyl-4-(2-dinitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester, C₁₇H₁₈N₂O₆.

ΚΠ

1971 Approved Names 1970 (Brit. Pharmacopœia Comm.) Suppl. iii Nifedipine.

1977 Lancet 29 Jan. 230/1 Such potent inhibitors of transcellular calcium migration as verapamil, prenylamine, and nifedipine decrease coronary-artery tone in vitro.

1989 Brit. Med. Jrnl. 6 May 1252/3 Calcium antagonists such as nifedipine..have become the treatment of choice for Raynaud's phenomenon.

2001 N. Jones Rough Guide Trav. Health i. 68 Nifedipine is normally used for the treatment of high blood pressure and angina, but it can be used as a prophylactic against mountain sickness, or as a treatment in acute episodes.

This is a new entry (OED Third Edition, September 2003; most recently modified version published online March 2022).

单词	nifedipine
释义	nifedipinen. Brit. /nʌɪˈfɛdᵻpiːn/, U.S. /ˌnaɪˈfɛdəˌpin/ Origin: Formed within English, by compounding. Etymons: nitro- comb. form, phenyl n., -dipine comb. form. Etymology: < ni- (in nitro- comb. form) + fe- (representing phenyl n.) + -dipine comb. form (contraction of dihydropyridine n.). Pharmacology. A dihydropyridine calcium channel blocker, used chiefly for the treatment of hypertension, angina pectoris, and Raynaud's phenomenon; 1,4-dihydro-2,6-dimethyl-4-(2-dinitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester, C₁₇H₁₈N₂O₆. ΚΠ 1971 Approved Names 1970 (Brit. Pharmacopœia Comm.) Suppl. iii Nifedipine. 1977 Lancet 29 Jan. 230/1 Such potent inhibitors of transcellular calcium migration as verapamil, prenylamine, and nifedipine decrease coronary-artery tone in vitro. 1989 Brit. Med. Jrnl. 6 May 1252/3 Calcium antagonists such as nifedipine..have become the treatment of choice for Raynaud's phenomenon. 2001 N. Jones Rough Guide Trav. Health i. 68 Nifedipine is normally used for the treatment of high blood pressure and angina, but it can be used as a prophylactic against mountain sickness, or as a treatment in acute episodes. This is a new entry (OED Third Edition, September 2003; most recently modified version published online March 2022). < n.1971
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