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单词 nigericin
释义

nigericinn.

Brit. /nʌɪˈdʒɪərᵻsɪn/, U.S. /naɪˈdʒɪrəˌsɪn/
Origin: Probably from a proper name, combined with an English element. Etymons: proper name Nigeria , -mycin suffix.
Etymology: Probably < the name of Nigeria (see Nigerian n. and adj.), the country of origin of a soil sample containing a Streptomyces species, from which the antibiotic was isolated + -cin (in -mycin suffix).
Biochemistry.
An antibiotic obtained from Streptomyces hygroscopicus that is an ionophore for monovalent cations and is used chiefly as an experimental tool.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > antibiotics > [noun] > other antibiotics
pyocyanase1900
fumigatin1938
M and B1938
gramicidin1940
tyrocidine1940
tyrothricin1940
clavacin1942
fumigacin1942
streptothricin1942
aspergillic acid1943
aspergillin1943
clavatin1943
helvolic acid1943
streptomycin1944
subtilin1944
bacitracin1945
viridin1945
javanicin1946
nisin1947
nitrofurazone1947
polymyxin1947
aureomycin1948
chloramphenicol1949
clitocybin1949
neomycin1949
Terramycin1950
viomycin1950
cephalosporin1951
fumagillin1951
nigericin1951
achromycin1952
carbomycin1952
erythromycin1952
nystatin1952
oxytetracycline1952
tetracycline1952
chlortetracycline1953
nitrofurantoin1953
oligomycin1953
puromycin1953
bacteriocin1954
albomycin1955
spiramycin1955
valinomycin1955
amphotericin B1956
mitomycin1956
novobiocin1956
oleandomycin1956
paromomycin1956
vancomycin1956
kanamycin1957
macrolide1957
ristocetin1957
streptovaricin1957
ethionamide1959
rifamycin1959
strep1959
mithramycin1960
fucidin1961
virginiamycin1961
cephalothin1962
fusidic acid1962
nonactin1962
trimethoprim1962
daunomycin1963
lincomycin1963
anthracycline1964
cephaloridine1964
spectinomycin1964
doxycycline1966
rifampicin1966
minocycline1967
rifampin1968
Adriamycin1969
daunorubicin1969
ribostamycin1970
doxorubicin1971
tobramycin1971
milbemycin1975
fluoroquinolone1984
1951 R. L. Harned et al. in Antibiotics & Chemotherapy 1 594 (title) Nigericin, a new crystalline antibiotic from an unidentified Streptomyces.
1967 Proc. National Acad. Sci. U.S.A. 58 1954 Both the valinomycin and the nigericin classes of antibiotics induce alkali ion permeability in mitochondrial and other systems by carrying ions across lipid barriers as lipid-soluble complexes.
1978 Sci. Amer. Mar. 117/2 Nigericin, another ionophore, brings about an electrically neutral exchange of protons for potassium ions.
2000 Brit. Jrnl. Pharmacol. 130 1809 Intracellular alkalinization was induced by nigericin, a monovalent cation ionophore.
This is a new entry (OED Third Edition, September 2003; most recently modified version published online March 2022).
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n.1951
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