单词 | neoantigen |
释义 | > as lemmasneoantigen neoantigen n. Brit. /ˌniːəʊˈantᵻdʒ(ə)n/ , U.S. /ˌnioʊˈæn(t)ədʒ(ə)n/ , /ˌnioʊˈæn(t)əˌdʒɛn/ Immunology an antigen to which the immune system has not previously been exposed, esp. one that arises by alteration of host antigens by viral infection, neoplastic transformation, drug metabolism, etc.ΚΠ 1965 Proc. National Acad. Sci. U.S.A. 54 381 Such tumors have the virus-specific antigen(s) characteristic of that produced by SV40 virus (hereafter referred to as the SV40 neoantigen). 1993 S. J. Ettinger Pocket Compan. Textbk. Vet. Internal Med. cxx. 798 The drug may act directly as an antigen or may combine with host proteins as haptens to form neoantigens. 2001 Clin. Diagnostic & Lab. Immunol. 8 880 Evaluation of the T-cell immune response following primary antigenic challenge with a neoantigen is a critical aspect of assessment of the cellular immune response. < as lemmas |
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