nitroreductionn.
/ˌnʌɪtrəʊrᵻˈdʌkʃn/, U.S. /ˈˌnaɪtroʊrəˈdəkʃ(ə)n/, /ˈˌnaɪtroʊˌriˈdəkʃ(ə)n/ Biochemistry.
The reduction of a nitro group in an organic molecule, spec. as catalysed by a nitroreductase.
ΚΠ
1949 Arch. Biochem. 24 218 The influence of various enzymic substrates on this nitro reduction reaction was studied.
1957 Jrnl. Pharmacol. & Exper. Therapeutics 119 197 Little is known about the biochemical mechanism responsible for nitro reduction.
1971 Science 11 June 1098/2 The rate of nitroreduction of p-nitrobenzoic acid, an anaerobic system, was also measured.
2000 Nature 22 June 964/1 Metronidazole requires activation by nitroreduction for activity against anaerobic bacteria.
This is a new entry (OED Third Edition, December 2003; most recently modified version published online March 2022).
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n.1949