non-synonymousadj.
/ˌnɒnsᵻˈnɒnᵻməs/, U.S. /ˌnɑnsəˈnɑnəməs/ 1. Of two or more words, expressions, etc.: not having the same meaning.
ΚΠ
1951 Philos. Rev. 60 28 Whether..some nonsynonymous expressions might be thus interchangeable.
1965 B. Mates Elem. Logic v. 79 The indicated procedure can lead to different, and plainly non-synonymous, translations for the same formal sentence.
1992 N.Y. Rev. Bks. 14 May 51/1 If one imagines a set of five or six such non-synonymous expressions (some as general as words for ‘he’).
2. Genetics. Designating a point mutation (base-pair change) in a codon that results in a change in the amino acid produced during translation.
ΚΠ
1985 Proc. National Acad. Sci. U.S.A. 82 1741/1 The ratio of the number of nucleotide substitutions..is 2.0 for synonymous substitutions and 1.3 for nonsynonymous substitutions.
1996 Tissue Antigens 47 212 Analysis of the substitution pattern for human alleles shows an excess of non-synonymous changes to synonymous changes at antigen recognition sites.
This entry has been updated (OED Third Edition, December 2003; most recently modified version published online March 2022).
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adj.1951- get nowhere
- get of
- get of coal
- get off
- get off a person's case
- get off at edge etc
- get off at edge gateshead
- get off at edge hill
- get off at edge redfern
- get off by heart
- get off from
- get off it
- get off lightly
- get off my back
- get off my case!
- get off of
- get off on the right foot
- get off on the wrong foot
- get off one's arse
- get off one's ass
- get off one's backside
- get off one's bike
- get off one's mark
- get off one's perch
- get off scot-free