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单词 normoblast
释义

normoblastn.

Brit. /ˈnɔːmə(ʊ)blɑːst/, /ˈnɔːmə(ʊ)blast/, U.S. /ˈnɔrməˌblæst/
Origin: A borrowing from German. Etymon: German Normoblast.
Etymology: < German Normoblast (P. Ehrlich 1880, in Berliner klin. Wochenschr. 17 405/1) < normo- normo- comb. form + -blast -blast comb. form.
Medicine.
An immature, nucleated red blood cell of normal size, having cytoplasm that is basophilic, polychromatophilic, or acidophilic (orthochromatic), depending on its stage of development. Cf. megaloblast n.
ΘΚΠ
the world > life > the body > vascular system > blood > components of blood > blood corpuscle or plate > [noun] > red cells or corpuscles
globule1674
red corpuscle1747
red blood disc1835
red cell1843
red blood corpuscle1844
pneumocyte1872
poikilocyte1886
haematid1888
normoblast1889
polychromatic normoblast1899
normocyte1900
spherocyte1908
polychrome1909
siderocyte1915
reticulocyte1922
proerythroblast1927
target cell1938
acanthocyte1952
sideroblast1954
1889 A. B. McKee tr. J. Cohnheim Lect. Gen. Pathol. (ed. 2) I. 482 He [sc. Ehrlich] distinguishes several varieties of nucleated red blood-corpuscles according to their size,—some uniform with normal red corpuscles, termed by him normoblasts.
1891 Bull. Johns Hopkins Hosp. 2 87/2 There was..a moderate amount of nucleated red corpuscles, chiefly of small size, with intensely staining, round, somewhat refractive nuclei (‘normoblasts’, Ehrlich).
1930 A. A. Maximow & W. Bloom Text-bk. Histol. v. 114 In this way erythroblasts arise in which the protoplasm is purely acidophil, and stains a bright pink with the Romanowsky mixture. These cells are called orthochromatic erythroblasts or normoblasts.
1968 Jrnl. Pediatrics 73 133/2 Red blood cells in various stages of development from pronormoblasts to late normoblasts.
1984 J. R. Tighe & D. R. Davies Pathol. (ed. 4) xxiii. 216 In the bone marrow there are abnormal normoblasts.
2002 Blood 99 3005 The transition from proerythroblast to basophilic normoblast occurred later.
This entry has been updated (OED Third Edition, December 2003; most recently modified version published online March 2022).
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n.1889
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