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单词 olivopontocerebellar
释义

olivopontocerebellaradj.

Brit. /ˌɒlɪvəʊˌpɒntəʊsɛrᵻˈbɛlə/, U.S. /ˈˌɑləvoʊˌpɑn(t)oʊˌsɛrəˈbɛlər/
Origin: A borrowing from Latin, combined with English elements; modelled on a French lexical item. Etymons: olive n.1, -o- connective, Latin pont- , pōns , cerebellar adj.
Etymology: < olive n.1 + -o- connective + classical Latin pont-, pōns (see pons n.) + -o- connective + cerebellar adj., after French atrophie olivo-ponto-cerebelleuse (1900).
Medicine.
Of or relating to the olive, the pons, and cerebellum; spec. in olivopontocerebellar atrophy, loss of neurons in these regions of the brain, which produces such symptoms as ataxia, tremor, and involuntary movements, and is seen as a sporadic disorder or as one of a group of inherited (usually autosomal dominant) disorders.
ΚΠ
1923 Schweizer Arch. f. Neurol. u. Psychiatrie 13 684 (title) A case of olivo-pontine cerebellar atrophy.]
1926 Southern Med. Jrnl. 19 520/1 The chronically progressive syndromes associated with involuntary movements... Dejerine and Thomas' olivo-ponto-cerebellar atrophy, which has not hitherto been shown to be hereditary or familial.
1970 Medicine 49 227/1 The olivopontocerebellar atrophies (OPCA) are a group of diseases characterized by loss of neurons in the cerebellar cortex, basis pontis, and inferior olivary nuclei.
1994 Neurology 44 1738 Impaired executive system function could be explained by damage to olivopontocerebellar system control over cerebral cortical function.
2000 Pediatric Neurol. 23 357 We report a patient with a unique combination of clinical findings: XY sex reversal, spastic paraplegia, mental retardation, dysmorphism, and infantile-onset olivopontocerebellar hypoplasia.
This is a new entry (OED Third Edition, March 2004; most recently modified version published online March 2022).
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adj.1926
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