off-labeladj.adv.

Brit.

/ˌɒfˈleɪbl/, U.S.

/ˌɔfˈleɪb(ə)l/,

/ˌɑfˈleɪb(ə)l/

Origin: Formed within English, by derivation. Etymons: off- prefix, label n.¹

Etymology: < off- prefix + label n.¹

colloquial.

A. adj.

Relating to or designating the use of a substance, esp. a drug, for a purpose or in a circumstance other than those for which it is officially approved.

ΚΠ

1987 Advertiser (Adelaide) 30 Oct. 5/8 The amendments also propose to ban the mixing of chemicals and ‘off-label’ use, or use of chemicals on crops not listed under container labels.

1995 Time 18 Sept. 97/3 For years insurers have recognized the importance of off-label prescribing and have agreed to reimburse patients for their prescriptions.

2004 Wall St. Jrnl. 17 May (Central ed.) b1/5 Off-label drug use, that is, administering a drug for an illness the drug wasn't specifically approved to treat, isn't illegal and is common in medical fields in which doctors tend to experiment with the latest advances in therapy.

B. adv.

Of the use of a substance, esp. a drug: for a purpose or in a circumstance other than those for which it is officially approved.

ΚΠ

1990 Washington Post 26 June (Health Mag.) 16/1 Many cancer and AIDS patients have trouble with claims for expensive drugs prescribed ‘off-label’.

2001 Time 7 May 76/1 Children with severe anxiety disorders..are given antidepressants ‘off label’—in ways for which they were not specifically approved.

2005 Chicago Tribune (Midwest ed.) 16 Jan. xiii. 6/2 Hyalgan is injected into the site of the osteoarthritis (the FDA has approved it for use in the knees, but it is often injected, off-label, into other joints).

This is a new entry (OED Third Edition, June 2006; most recently modified version published online March 2022).

单词	off-label
释义	off-labeladj.adv. Brit. /ˌɒfˈleɪbl/, U.S. /ˌɔfˈleɪb(ə)l/, /ˌɑfˈleɪb(ə)l/ Origin: Formed within English, by derivation. Etymons: off- prefix, label n.¹ Etymology: < off- prefix + label n.¹ colloquial. A. adj. Relating to or designating the use of a substance, esp. a drug, for a purpose or in a circumstance other than those for which it is officially approved. ΚΠ 1987 Advertiser (Adelaide) 30 Oct. 5/8 The amendments also propose to ban the mixing of chemicals and ‘off-label’ use, or use of chemicals on crops not listed under container labels. 1995 Time 18 Sept. 97/3 For years insurers have recognized the importance of off-label prescribing and have agreed to reimburse patients for their prescriptions. 2004 Wall St. Jrnl. 17 May (Central ed.) b1/5 Off-label drug use, that is, administering a drug for an illness the drug wasn't specifically approved to treat, isn't illegal and is common in medical fields in which doctors tend to experiment with the latest advances in therapy. B. adv. Of the use of a substance, esp. a drug: for a purpose or in a circumstance other than those for which it is officially approved. ΚΠ 1990 Washington Post 26 June (Health Mag.) 16/1 Many cancer and AIDS patients have trouble with claims for expensive drugs prescribed ‘off-label’. 2001 Time 7 May 76/1 Children with severe anxiety disorders..are given antidepressants ‘off label’—in ways for which they were not specifically approved. 2005 Chicago Tribune (Midwest ed.) 16 Jan. xiii. 6/2 Hyalgan is injected into the site of the osteoarthritis (the FDA has approved it for use in the knees, but it is often injected, off-label, into other joints). This is a new entry (OED Third Edition, June 2006; most recently modified version published online March 2022). < adj.adv.1987
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