opioidn.adj.

Brit.

/ˈəʊpɪɔɪd/, U.S.

/ˈoʊpiˌɔɪd/

Origin: Formed within English, by derivation. Etymons: opium n., -oid suffix.

Etymology: < opium n. + -oid suffix.

Pharmacology and Biochemistry.

A. n.

Originally: any synthetic narcotic drug derived from or having properties similar to those of morphine. Later also: an opiate (opiate n. 1a).

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics

Hoffmann's anodyne1747

acetylsalicylic acid1873

acetophenetidin1888

exalgin1889

pyramidon1898

aspirin1899

phenazone1899

Veganin1926

Trilene1935

Demerol1940

pethidine1942

Tridione1944

amidone1946

meperidine1947

methadone1947

Physeptone1947

Butazolidin1951

phenylbutazone1952

opioid1955

Panadol1955

propoxyphene1955

Tylenol1956

acetaminophen1957

paracetamol1957

Distalgesic1958

oxycodone1958

Sernyl1958

morphinomimetic1959

phencyclidine1959

levorphanol1960

mefenamic acid1962

pentazocine1964

Talwin1965

ibuprofen1967

nalbuphine1969

naproxen1971

phy1971

Nurofen1982

the world > physical sensation > use of drugs and poison > an intoxicating drug > [noun] > a) narcotic drug(s) > opium > drug similar to opium

opiate?a1425

opioid1955

1955 E. G. Gross & M. J. Schiffrin Clin. Analgetics i. 4 Acheson and Pfeiffer have recently suggested that the term ‘opioid’ be used in lieu of ‘synthetic opiate-like compounds’.

1957 Pharmaceut. Jrnl. 179 321/1 Acheson has suggested that the morphinans and other synthetic morphine substitutes should be called opioids.

1974 M. C. Gerald Pharmacol. xiii. 237 Synthetic narcotic agents or opioids, which bear only highly subtle similarities to the structure of morphine.

1986 Fortune 18 Aug. 33/1 Among other things, opioids relieve pain and affect bowel activity. Some opioids found in the hypothalamus..also appear to stimulate appetite.

2017 R. J. Bonnie et al. Pain Managem. & Opioid Epidemic Introd. 17 Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States.

B. adj.

Of, relating to, or of the nature of an opioid.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [adjective]

anodyne1543

paregorical1651

paregoric1678

antalgic1753

pain-killing1865

analgetic1867

opioid1959

morphinomimetic1968

1959 Jrnl. Amer. Dental Assoc. Apr. 29/1 The doses and some of the side effects of the opiate and opioid drugs are compared.

1967 Pharmacol. Rev. 19 464 We have adopted the term opioid, which was proposed by Professor George H. Acheson, to designate those analgesics whose pattern of pharmacological and agonistic effects is similar to that of morphine and..have called this pattern of effects the opioid syndrome.

1976 H. W. Kosterlitz (title) Opiates and endogenous opioid peptides.

1981 Brain Res. Bull. 7 279 The prototype σ opioid receptor agonist N-allyl-normetazocine..was injected into the third cerebral ventricle of..cats.

2001 Esquire Aug. 117/2 Vicodin is not legally available in Britain, because such ‘opioid analgesics’ are classed as controlled drugs.

This entry has been updated (OED Third Edition, June 2004; most recently modified version published online March 2022).

单词	opioid
释义	opioidn.adj. Brit. /ˈəʊpɪɔɪd/, U.S. /ˈoʊpiˌɔɪd/ Origin: Formed within English, by derivation. Etymons: opium n., -oid suffix. Etymology: < opium n. + -oid suffix. Pharmacology and Biochemistry. A. n. Originally: any synthetic narcotic drug derived from or having properties similar to those of morphine. Later also: an opiate (opiate n. 1a). ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics Hoffmann's anodyne1747 acetylsalicylic acid1873 acetophenetidin1888 exalgin1889 pyramidon1898 aspirin1899 phenazone1899 Veganin1926 Trilene1935 Demerol1940 pethidine1942 Tridione1944 amidone1946 meperidine1947 methadone1947 Physeptone1947 Butazolidin1951 phenylbutazone1952 opioid1955 Panadol1955 propoxyphene1955 Tylenol1956 acetaminophen1957 paracetamol1957 Distalgesic1958 oxycodone1958 Sernyl1958 morphinomimetic1959 phencyclidine1959 levorphanol1960 mefenamic acid1962 pentazocine1964 Talwin1965 ibuprofen1967 nalbuphine1969 naproxen1971 phy1971 Nurofen1982 the world > physical sensation > use of drugs and poison > an intoxicating drug > [noun] > a) narcotic drug(s) > opium > drug similar to opium opiate?a1425 opioid1955 1955 E. G. Gross & M. J. Schiffrin Clin. Analgetics i. 4 Acheson and Pfeiffer have recently suggested that the term ‘opioid’ be used in lieu of ‘synthetic opiate-like compounds’. 1957 Pharmaceut. Jrnl. 179 321/1 Acheson has suggested that the morphinans and other synthetic morphine substitutes should be called opioids. 1974 M. C. Gerald Pharmacol. xiii. 237 Synthetic narcotic agents or opioids, which bear only highly subtle similarities to the structure of morphine. 1986 Fortune 18 Aug. 33/1 Among other things, opioids relieve pain and affect bowel activity. Some opioids found in the hypothalamus..also appear to stimulate appetite. 2017 R. J. Bonnie et al. Pain Managem. & Opioid Epidemic Introd. 17 Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. B. adj. Of, relating to, or of the nature of an opioid. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [adjective] anodyne1543 paregorical1651 paregoric1678 antalgic1753 pain-killing1865 analgetic1867 opioid1959 morphinomimetic1968 1959 Jrnl. Amer. Dental Assoc. Apr. 29/1 The doses and some of the side effects of the opiate and opioid drugs are compared. 1967 Pharmacol. Rev. 19 464 We have adopted the term opioid, which was proposed by Professor George H. Acheson, to designate those analgesics whose pattern of pharmacological and agonistic effects is similar to that of morphine and..have called this pattern of effects the opioid syndrome. 1976 H. W. Kosterlitz (title) Opiates and endogenous opioid peptides. 1981 Brain Res. Bull. 7 279 The prototype σ opioid receptor agonist N-allyl-normetazocine..was injected into the third cerebral ventricle of..cats. 2001 Esquire Aug. 117/2 Vicodin is not legally available in Britain, because such ‘opioid analgesics’ are classed as controlled drugs. This entry has been updated (OED Third Edition, June 2004; most recently modified version published online March 2022). < n.adj.1955
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