osteogenesis imperfectan.

Brit.

/ˌɒstɪəʊˈdʒɛnᵻsɪs ˌɪmpəˈfɛktə/, U.S.

/ˈˌɑstioʊˈdʒɛnəsəs ˌɪmpərˈfɛktə/

Origin: A borrowing from Latin. Etymon: Latin osteogenesis imperfecta.

Etymology: < scientific Latin osteogenesis imperfecta (W. Vrolik Tabulæ Illustrandam Embryogenesin Hominis et Mammalium (1849) tab. 91) < scientific Latin osteogenesis osteogenesis n. + classical Latin imperfecta , feminine singular of imperfectus imperfect adj.

Medicine.

Any of various disorders characterized by defective formation of bone; spec. any of a group of inherited (autosomal dominant or autosomal recessive) disorders characterized by defective synthesis of type I collagen, resulting in brittle bones that fracture easily.

ΘΚΠ

the world > health and disease > ill health > a disease > diseases of tissue > disorders of bones > [noun] > other bone disorders

osteocachexy1857

osteitis deformans1877

Paget's disease1889

megalacria1891

osteochondritis dissecans1895

osteogenesis imperfecta1899

von Recklinghausen's disease1910

Albright's syndrome1940

fibrogenesis imperfecta ossium1952

pycnodysostosis1963

McCune–Albright syndrome1966

1899 J. W. Ballantyne in W. A. Edwards Cycl. Dis. Children V. 12 We have not yet reached the time when a scientific classification of fœtal bone diseases on pathological lines is possible, and we must therefore be content with such a general denomination as osteogenesis imperfecta.

1903 Amer. Jrnl. Med. Sci. 125 762 The disease called by Vrolik and by Stilling osteogenesis imperfecta, which previously in all probability was classed under fœtal rickets, is a definite, intrauterine process, the chief characteristics of which are great brittleness and softness of the bones, numerous fractures, and resulting deformities, due to as yet obscure disturbances of myelogenic and periosteal bone formation.

1923 Brit. Jrnl. Surg. 11 737 Osteogenesis imperfecta is the name given to a disease which is characterized by a congenital defect in the evolution of the osteoblast, and recognized clinically by defective ossification of the cranium and a multiplicity of fractures resulting from trivial causes.

1988 Woman's Day (N.Y.) Jan. 131/1 The oldest of their three children..suffers from an unpronounceable disease (osteogenesis imperfecta) that causes frequent fractures of his soft, brittle bones.

2002 Sun 25 Sept. 13/2 Julie says: ‘I was born ten weeks prematurely with osteogenesis imperfecta, or brittle bone disease as it's more commonly known.’

This entry has been updated (OED Third Edition, September 2004; most recently modified version published online March 2022).

单词	osteogenesis imperfecta
释义	osteogenesis imperfectan. Brit. /ˌɒstɪəʊˈdʒɛnᵻsɪs ˌɪmpəˈfɛktə/, U.S. /ˈˌɑstioʊˈdʒɛnəsəs ˌɪmpərˈfɛktə/ Origin: A borrowing from Latin. Etymon: Latin osteogenesis imperfecta. Etymology: < scientific Latin osteogenesis imperfecta (W. Vrolik Tabulæ Illustrandam Embryogenesin Hominis et Mammalium (1849) tab. 91) < scientific Latin osteogenesis osteogenesis n. + classical Latin imperfecta , feminine singular of imperfectus imperfect adj. Medicine. Any of various disorders characterized by defective formation of bone; spec. any of a group of inherited (autosomal dominant or autosomal recessive) disorders characterized by defective synthesis of type I collagen, resulting in brittle bones that fracture easily. ΘΚΠ the world > health and disease > ill health > a disease > diseases of tissue > disorders of bones > [noun] > other bone disorders osteocachexy1857 osteitis deformans1877 Paget's disease1889 megalacria1891 osteochondritis dissecans1895 osteogenesis imperfecta1899 von Recklinghausen's disease1910 Albright's syndrome1940 fibrogenesis imperfecta ossium1952 pycnodysostosis1963 McCune–Albright syndrome1966 1899 J. W. Ballantyne in W. A. Edwards Cycl. Dis. Children V. 12 We have not yet reached the time when a scientific classification of fœtal bone diseases on pathological lines is possible, and we must therefore be content with such a general denomination as osteogenesis imperfecta. 1903 Amer. Jrnl. Med. Sci. 125 762 The disease called by Vrolik and by Stilling osteogenesis imperfecta, which previously in all probability was classed under fœtal rickets, is a definite, intrauterine process, the chief characteristics of which are great brittleness and softness of the bones, numerous fractures, and resulting deformities, due to as yet obscure disturbances of myelogenic and periosteal bone formation. 1923 Brit. Jrnl. Surg. 11 737 Osteogenesis imperfecta is the name given to a disease which is characterized by a congenital defect in the evolution of the osteoblast, and recognized clinically by defective ossification of the cranium and a multiplicity of fractures resulting from trivial causes. 1988 Woman's Day (N.Y.) Jan. 131/1 The oldest of their three children..suffers from an unpronounceable disease (osteogenesis imperfecta) that causes frequent fractures of his soft, brittle bones. 2002 Sun 25 Sept. 13/2 Julie says: ‘I was born ten weeks prematurely with osteogenesis imperfecta, or brittle bone disease as it's more commonly known.’ This entry has been updated (OED Third Edition, September 2004; most recently modified version published online March 2022). < n.1899
随便看	nodule noduled nodules noduliferous noduliform nodulization nodulize nodulized nodulizing nodulose nodulous nodulus nodum nodus nody noegenesis noegenetic noel noels noema noemata noematic noematical noematically noeme