osteosclerosisn.

1841 Brit. & Foreign Med. Rev. 12 158 Osteosclerosis, or hardening of bone, is exactly the opposite of the last considered affection [sc. mollities ossium].

1855 G. Busk tr. C. Wedl Rudim. Pathol. Histol. 492 A hypertrophy of the bone-corpuscles, and of the so-termed osseous lamellæ (osteosclerosis).

1901 Brit. Med. Jrnl. 29 June 1604 The bones [in general paralysis of the insane] generally show a high degree of osteo-sclerosis.

1938 Lancet 26 Nov. 1229/2 Osteosclerosis literally means a hardening of bone, but the term is generally used, regardless of the physical state, to signify bone which casts a dense shadow in a radiogram.

1968 Science 29 Mar. 1494/2 Pinet..studied non-crippling osteosclerosis in the Sahara.

1995 Independent 24 Jan. 23/4 If our diet contains too much fluoride, we may suffer from fluorosis, the first signs of which are mottled teeth. Later there may be osteosclerosis—hardening of the bones which leads to a deformed skeleton.