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单词 paroxetine
释义

paroxetinen.

Brit. /pəˈrɒksətiːn/, U.S. /pərˈɑksəˌtin/
Origin: Apparently formed within English, by derivation. Etymons: para- prefix1, oxy- comb. form2, piperidine n.
Etymology: Apparently < par- (in para- prefix1) + ox- (in oxy- comb. form2) + -et- (perhaps an arbitrary element) + -ine (in piperidine n.), representing components of the molecular structure.
Pharmacology.
An antidepressant that is a selective serotonin reuptake inhibitor and is also used for the treatment of anxiety disorders.A proprietary name for this drug is Seroxat. Chemical name: (−)-trans-4-(p-fluorophenyl)-3-{[3,4-(methylenedioxy)phenoxy]-methyl}piperidine.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > antidepressant > specific drugs
Marsilid1952
iproniazid1953
levallorphan1953
imipramine1958
Tofranil1958
isocarboxazid1959
Marplan1959
Nardil1959
nialamide1959
Niamid1959
phenelzine1959
tranylcypromine1959
Parnate1960
amitriptyline1961
monoamine oxidase inhibitor1962
nortriptyline1962
protriptyline1963
MAOI1965
maprotiline1970
mianserin1970
amoxapine1971
fluoxetine1975
paroxetine1977
Prozac1985
Seroxat1985
1977 WHO Chron. 31 ix. 14 Paroxetine... C19H20FNO3.
1978 Psychopharmacol. (Berlin) 57 151 The previous and present results indicate that paroxetine is a selective 5-HT-uptake inhibitor.
1989 Jrnl. Psychopharmacol. 3 24P Paroxetine, a new clinically effective antidepressant.
1998 Daily Tel. 9 Oct. 9/1 Paroxetine, already licensed for the treatment of depression, was launched yesterday to treat ‘social anxiety disorder’.
2001 New Scientist 24 Mar. 48/3 The SSRIs such as fluoxetine (Prozac), sertraline, paroxetine and so on all boost levels of the neurotransmitter serotonin.
This is a new entry (OED Third Edition, June 2005; most recently modified version published online March 2022).
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n.1977
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