parasympatholyticadj.n.
/ˌparəsɪmpəθəʊˈlɪtɪk/, U.S. /ˈˌpɛrəˌsɪmpəθoʊˈlɪdɪk/ Pharmacology and Physiology.
A. adj.
Blocking or opposing the effects of parasympathetic nerve stimulation; anticholinergic.
ΘΚΠ
the world > health and disease > healing > medicines or physic > drugs having specific effect > [adjective] > parasympatholytic
parasympatholytic1946
1946 Science 5 Apr. 411/2 The acute pharmacological actions of the mustards... Prominent among these are..parasympathomimetic effects as evidenced by salivation, miosis, etc., followed by a parasympatholytic action.
1960 A. Burger Medicinal Chem. (ed. 2) liii. 1147/2 Diphemanil methylsulfate is a parasympatholytic agent which blocks the cholinergic impulse to the eccrine sweat glands.
1995 Ophthalmologica 209 223 The pupillary block observed in our case may be the result of the serotoninergic or indirect parasympatholytic properties of the drug [sc. dexfenfluramine] on the iris sphincter muscle.
B. n.
A parasympatholytic agent.
ΘΚΠ
the world > health and disease > healing > medicines or physic > drugs having specific effect > [noun] > parasympatholytic
parasympatholytic1959
1959 Science 8 May 1262/3 Three groups of compounds..: the parasympatholytics (scopolamine and atropine), the central ganglioplegic..drugs, and the neuroleptics.
1995 Vet. Rec. 137 183/1 Two aerosolised bronchodilators, one sympathomimetic and one parasympatholytic, were tested..for their ability to improve the pulmonary function of double-muscled calves suffering from acute respiratory distress syndrome.
This entry has been updated (OED Third Edition, June 2005; most recently modified version published online March 2022).
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