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单词 parasynaptic
释义

parasynapticadj.

Brit. /ˌparəsᵻˈnaptɪk/, U.S. /ˈˌpɛrəsəˈnæptɪk/
Origin: Formed within English, by derivation. Etymons: para- prefix1, synaptic adj.
Etymology: < para- prefix1 + synaptic adj., after parasynapsis n.
1. Cell Biology. Of, relating to, or involving parasynapsis. Now rare or disused.
ΘΚΠ
the world > life > biology > biological processes > genetic activity > [adjective] > other processes in mitosis or meiosis
parasynaptic1910
non-disjunctional1913
asynaptic1937
stathmokinetic1939
1910 Ann. Bot. 24 727 Grégoire.., while agreeing with the parasynaptic chromosome formation, put a different interpretation on to the ‘gamosomes’ and ‘zygosomes’ of Strasburger and Miyake.
1912 Jrnl. Exper. Zool. 13 394 Bivalent segments, each consisting of two chromosomes in parasynaptic union.
1921 Ann. Bot. 35 386 Both the telosynaptic and the parasynaptic methods of synapsis may occur, the latter perhaps more largely in forms with long thready chromosomes and the former with short and stout chromosomes.
1929 Jrnl. Genetics 21 46 In Prunus cerasus..the method of pairing is parasynaptic, judging from the occurrence of diplotene chiasmata and their occasional persistence to metaphase as interstitial exchanges.
1945 Science 28 Dec. 656/2 All unions of chromosomes are end to end and parallel or so-called parasynaptic unions do not occur.
2. Biology.
a. Situated or occurring near a synapse.
ΚΠ
1981 Arch. Pathol. & Lab. Med. 105 334 (title) Parasynaptic corpora amylacea in the striatum.
1999 Proc. National Acad. Sci. U.S.A. 96 1100/1 N-cadherin and its intracellular binding partners α- and β-catenin are expressed in a parasynaptic manner flanking release sites.
b. Acting upon neurons or the nervous system at a site other than a synapse; involving or relating to such activity.
ΚΠ
1984 F. O. Schmitt in Neuroscience 13 995/2 The parasynaptic mode involves the diffusion of ISs [= informational substances] from release sites, through ECF to target cells that possess specific receptors for ISs. The term parasynaptic connotes processes that occur ‘in parallel with’ or ‘alongside’ neuronal circuitry.
1992 S. S. Hall Mapping Next Millennium (1993) viii. 170 Schmitt..argues that many molecules in the brain act at a distance rather than directly at the synapse; he proposes the term ‘parasynaptic’ to describe this type of long-distance chemical signaling.
1999 Brain Res. Bull. 50 351 (title) Extrasynaptic receptors and parasynaptic communication in the brain.

Derivatives

parasyˈnaptically adv.
ΘΚΠ
the world > life > biology > biological processes > genetic activity > [adverb] > other processes
parasynaptically1910
parasyndetically1911
tandemly1968
1910 Ann. Bot. 24 752 Whether these univalent strands join with their homologous pairs telosynaptically or parasynaptically, or by any other intermediate method between these two extremes, resolves itself merely into a question of non-essential detail.
1933 Proc. Royal Soc. B. 113 67 How would 14 chromosome threads associate parasynaptically in early prophase?
1997 European Jrnl. Neurosci. 9 128 An important contingent was detected opposite non-axonal elements, such as dendrites and glial cells, suggesting that mu opioid ligands act mainly parasynaptically on locus coeruleus neurons.
This entry has been updated (OED Third Edition, June 2005; most recently modified version published online March 2022).
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adj.1910
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