单词 | pellagra |
释义 | pellagran. Medicine. A condition caused by deficiency of the B-complex vitamin nicotinic acid (niacin) or its precursor, the amino acid tryptophan, characterized by dermatitis, diarrhoea, and mental disturbance, and often linked to over-dependence on maize as a staple food. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disordered nutrition > [noun] > diseases of malnutrition pellagra1811 1811 R. Hooper Quincy's Lexicon-medicum (new ed.) (at cited word) The disease called the pelagra does not appear to have been noticed by any of our nosologists. 1826 Lancet 21 Oct. 75/2 All kinds of patients are received, excepting those affected with pellagra, that pest of northern Italy. 1874 J. C. Bucknill & D. H. Tuke Man. Psychol. Med. (ed. 3) 364 The first descriptions of pellagra appear about the year 1770. 1894 Amer. Naturalist 28 972 Some of the peasants eat maize in the common form of Polenta (boiled mush) to such an extent..that a sickness called Pelagra, showing itself in shrunken skin, emaciation, dizziness, intense thirst, and a desire to plunge into pools of water, is the result. 1919 Jrnl. Amer. Folk-lore 32 392 Poplar-bark is steeped for pelagra. 1941 J. Agee & W. Evans Let us now praise Famous Men 119 His wife's pellagra got into her brain. 1993 Independent on Sunday 5 Sept. (Review Suppl.) 53/4 Lack of vitamins may, they say, produce dramatic diseases such as scurvy, beri-beri and pellagra, but these conditions are virtually unknown in Western countries except in eccentrics, alcoholics and people with mental disorders. Compounds pellagra-preventive factor n. either of the B-complex vitamins niacin and niacinamide; also called P-P factor. ΚΠ 1925 Public Health Rep. (U.S. Public Health Service) 40 77 It would seem as if the heretofore unrecognized pellagra-preventive factor, to which we shall hereafter refer to as factor P-P, were capable of preventing the disease with little or no cooperation from the protein factor of the diet. 1987 Egyptian Jrnl. Pharmaceutical Sci. 27 227 A rapid quantitative gas-liquid chromatographic (GLC) method for the determination of the pellagra-preventive factor nicotinic acid (niacin)..is developed. This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022). < n.1811 |
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