pentoliniumn.

Brit.

/ˌpɛntəˈlɪnɪəm/,

/ˌpɛntlˈɪnɪəm/, U.S.

/ˌpɛn(t)lˈɪniəm/

Origin: Formed within English, by derivation. Etymons: pentamethylene n. at penta- comb. form 2b, pyrrolidine n., -ium suffix.

Etymology: < pent- (in pentamethylene n. at penta- comb. form 2b) + -ol- and -in- (in pyrrolidine n.) + -ium suffix (see quot. 1954).

Pharmacology.

A ganglion-blocking agent originally used in the treatment of severe hypertension; pentamethylene-1,5-bis-(1-methyl-pyrrolidinium) hydrogen tartrate, C₂₃H₄₂N₂O₁₂. More fully pentolinium tartrate.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders

Neo-Synephrine1934

Priscol1938

phenylephrine1947

hexamethonium1949

Priscoline1949

methonium1950

hydralazine1952

phentolamine1953

methyldopa1954

pentolinium1954

mecamylamine1955

hydrochlorothiazide1958

pempidine1958

guanethidine1959

hydroflumethiazide1959

thiazide1959

pheniprazine1960

pargyline1961

vasodepressor1961

alpha blocker1965

clonidine1969

prazosin1970

timolol1973

1954 Lancet 27 Nov. 1097/2 The preparation used was ‘Ansolysen’.., termed pentolinium tartrate by the British Pharmacopœia Commission in 1954.

1974 Prescribers Jrnl. 14 47 Ganglion blocking drugs, such as pentolinium..and pempidine.., have been omitted from this short review because..they have now been largely superseded.

1990 Philos. Trans. (Royal Soc.) B. 330 394 Pentolinium is selective for ganglionic nicotinic receptors, while the other three have mainly neuromuscular actions.

This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022).

单词	pentolinium
释义	pentoliniumn. Brit. /ˌpɛntəˈlɪnɪəm/, /ˌpɛntlˈɪnɪəm/, U.S. /ˌpɛn(t)lˈɪniəm/ Origin: Formed within English, by derivation. Etymons: pentamethylene n. at penta- comb. form 2b, pyrrolidine n., -ium suffix. Etymology: < pent- (in pentamethylene n. at penta- comb. form 2b) + -ol- and -in- (in pyrrolidine n.) + -ium suffix (see quot. 1954). Pharmacology. A ganglion-blocking agent originally used in the treatment of severe hypertension; pentamethylene-1,5-bis-(1-methyl-pyrrolidinium) hydrogen tartrate, C₂₃H₄₂N₂O₁₂. More fully pentolinium tartrate. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders Neo-Synephrine1934 Priscol1938 phenylephrine1947 hexamethonium1949 Priscoline1949 methonium1950 hydralazine1952 phentolamine1953 methyldopa1954 pentolinium1954 mecamylamine1955 hydrochlorothiazide1958 pempidine1958 guanethidine1959 hydroflumethiazide1959 thiazide1959 pheniprazine1960 pargyline1961 vasodepressor1961 alpha blocker1965 clonidine1969 prazosin1970 timolol1973 1954 Lancet 27 Nov. 1097/2 The preparation used was ‘Ansolysen’.., termed pentolinium tartrate by the British Pharmacopœia Commission in 1954. 1974 Prescribers Jrnl. 14 47 Ganglion blocking drugs, such as pentolinium..and pempidine.., have been omitted from this short review because..they have now been largely superseded. 1990 Philos. Trans. (Royal Soc.) B. 330 394 Pentolinium is selective for ganglionic nicotinic receptors, while the other three have mainly neuromuscular actions. This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022). < n.1954
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