pentylenetetrazoln.
/ˌpɛntᵻliːnˈtɛtrəzɒl/, U.S. /ˈˌpɛn(t)əˌlinˈtɛtrəˌzɔl/, /ˈˌpɛn(t)əˌlinˈtɛtrəˌzɑl/ Pharmacology.
A synthetic, crystalline, neutral compound having a bicyclic molecular structure, used as a central nervous system and respiratory stimulant; 1,5-pentamethylenetetrazole, C6H10N4. Also called leptazol.A proprietary name for this drug is Metrazol.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > restoratives, tonics, or stimulants > [noun] > restorative > specific drug
Coramine1925
Metrazol1928
nikethamide1940
pentylenetetrazol1949
Regaine1985
Rogaine1986
1949 Blakiston's New Gould Med. Dict. 745/2 Pentylenetetrazol. See metrazol.
1953 Med. Ann. District of Columbia 22 175 (title) The effect of oral administration of pentylenetetrazol and barbiturate combinations.
1974 M. C. Gerald Pharmacol. xv. 292 We may categorize..pentylenetetrazol (metrazol), picrotoxin,..as midbrain or brain stem stimulants.
1989 Sci. Amer. June 91/1 Early difficulties in dosage regulation..were avoided by substituting first intravenous pentylenetetrazole and then inhalation of hexafluorodiethyl ether.
2004 Psychiatric Times (Nexis) 1 Feb. 93 The first of the convulsive therapies was initiated in 1934 in Budapest, Hungary. It entailed inducing convulsions with pentylenetetrazol, a compound first introduced as a cardiac drug.
This is a new entry (OED Third Edition, September 2005; most recently modified version published online March 2022).
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n.1949