phagemidn.

Brit.

/ˈfeɪdʒəmɪd/, U.S.

/ˈfeɪdʒəˌmɪd/

Origin: Formed within English, by blending. Etymons: phage n., plasmid n.

Etymology: < phage n. + -mid (in plasmid n.).

Genetics.

A genetically engineered stretch of DNA combining DNA sections from a plasmid with those from a phage, for use as a cloning vector. Frequently attributive.

ΚΠ

1984 A. A. Melnikov et al. in Gene 28 29 We call these DNA hybrids ‘phagemids’. This word clearly reflects the dual functional activities of the phage-plasmid DNA hybrids.

1985 Proc. National Acad. Sci. U.S.A. 82 5973 We used three λ mini-F phagemids—that is, λ vectors carrying mini-F (i) λML31:Kan^R.., (ii) λpSC138:Amp^R.., and (iii) λpSC138Ham22.

1990 Mutagenesis 5 606/2 The 1.25 kb insert from the longest of these clones was subcloned in pTZ phagemid vectors and sequenced completely.

2002 Biochemistry 41 14255 Modified and unmodified oligomers inserted into single-stranded phagemid shuttle vectors were used to transform E. coli or to transfect COS-7 cells.

This is a new entry (OED Third Edition, December 2005; most recently modified version published online March 2022).

单词	phagemid
释义	phagemidn. Brit. /ˈfeɪdʒəmɪd/, U.S. /ˈfeɪdʒəˌmɪd/ Origin: Formed within English, by blending. Etymons: phage n., plasmid n. Etymology: < phage n. + -mid (in plasmid n.). Genetics. A genetically engineered stretch of DNA combining DNA sections from a plasmid with those from a phage, for use as a cloning vector. Frequently attributive. ΚΠ 1984 A. A. Melnikov et al. in Gene 28 29 We call these DNA hybrids ‘phagemids’. This word clearly reflects the dual functional activities of the phage-plasmid DNA hybrids. 1985 Proc. National Acad. Sci. U.S.A. 82 5973 We used three λ mini-F phagemids—that is, λ vectors carrying mini-F (i) λML31:Kan^R.., (ii) λpSC138:Amp^R.., and (iii) λpSC138Ham22. 1990 Mutagenesis 5 606/2 The 1.25 kb insert from the longest of these clones was subcloned in pTZ phagemid vectors and sequenced completely. 2002 Biochemistry 41 14255 Modified and unmodified oligomers inserted into single-stranded phagemid shuttle vectors were used to transform E. coli or to transfect COS-7 cells. This is a new entry (OED Third Edition, December 2005; most recently modified version published online March 2022). < n.1984
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