单词 | phenome |
释义 | phenomen. Biology. Originally: the sum total of the constituents of a cell exclusive of its genetic material (rare). Now more widely: the phenotypic counterpart or expression of the genome; the complete set of phenotypic characteristics of an organism. ΚΠ 1949 B. D. Davis in Proc. National Acad. Sci. U.S.A. 35 8 We here propose the name phenome for the sum total of extragenic, non-autoreproductive portions of the cell, whether cytoplasmic or nuclear. 1964 Systematic Zool. 13 114/2 The idea that in studying characters of the phenome (the phenotypic analog of the genome—Soulé, 1964) we are attempting to sample the genome has been stated explicitly. 1967 Amer. Naturalist 101 157 Asymmetry could become a very powerful tool, not only for developmental biologists but also for those population biologists interested in the interplay between genome, phenome (the phenotype as a whole), and environment. 1987 Q. Rev. Biol. 62 292/1 If genomes were blueprints for phenomes such that a one-to-one isomorphism existed between the two, then mechanisms might exist for reading phenotypic changes back into genotypes. 2003 Nature Genetics 34 15 We propose an international effort to create..comprehensive assemblages of systematically collected phenotypic information, and to develop new approaches for analyzing such phenotypic data. We term this effort the Human Phenome Project. This is a new entry (OED Third Edition, December 2005; most recently modified version published online March 2022). < n.1949 |
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