单词 | phenytoin |
释义 | phenytoinn. Pharmacology. An anticonvulsant drug; (more fully phenytoin sodium) the sodium salt of this.Chemical name: 5,5-diphenylhydantoin, C15H12N2O2. A proprietary name for this drug in the United States is Dilantin n. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > antispasmodic or anticonvulsant > specific substances or preparations Dilantin1938 phenytoin1942 Artane1948 Mysoline1949 mephenesin1952 troxidone1952 primidone1953 acetazolamide1954 orphenadrine1957 tetrabenazine1958 ethosuximide1960 methsuximide1965 clonazepam1970 valproic1972 valproate1974 1942 Jrnl. Amer. Med. Assoc. 4 Apr. 1209/2 While phenytoin sodium (sodium diphenyl hydrantoinate, or dilantin sodium) was effective in protecting animals from electrically induced convulsions it produced little sedative effect. 1952 A. H. Douthwaite Hale-White's Mat. Med. (ed. 29) 193 When grand mal and petit mal occur in the same patient phenobarbitone and troxidone should be used together: phenytoin must not be employed. 1968 Brain 91 202 In 1956, Girdwood and Lenman first drew attention to certain structural similarities between phenobarbitone, phenytoin, primidone and folic acid. 1995 Family Health Spring 17/3 Phenytoin (Dilantin), Phenobarbital, and Valproic Acid are drugs used to control seizures in epilepsy and are all Category D. This entry has been updated (OED Third Edition, December 2005; most recently modified version published online March 2022). < n.1942 |
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