Philadelphian.

1788 Columbian Mag. Apr. 182 They have a proverb here [i.e. in London], which I do not know how to account for;—in speaking of a difficult point, they say, it would puzzle a Philadelphia lawyer.

1803 Balance (Hudson, N.Y.) 15 Nov. 363/1 It would (to use a Yankee phrase) puzzle a dozen Philadelphia lawyers to unriddle the conduct of the democrats.

1834 W. G. Simms Guy Rivers II. i. 23 You would have made a prime counsellor..worthy of the Philadelphia lawyers.

1872 C. W. Stearns Black Man of South 389 It would have required the genius of a ‘Philadelphia lawyer’, to have made a plain story out the complicated snarl of their family arrangements.

1909 L. M. Montgomery Anne of Avonlea xxvi. 306 I won't undertake to answer Davy's questions... I'm not an encyclopedia, neither am I a Philadelphia lawyer.

1947 Daily Times (Chicago) 28 Nov. 14/3 The new violation ticket will be in quadruplicate, and traffic officials say it takes a ‘Philadelphia lawyer’ to fix it.

1994 D. Goold How to get what you want from your Bank ii. 60 Be a Philadelphia lawyer. Read the fine print of whatever loan document is shoved under your nose, and ask for a full explanation of any points you don't understand.

1961 I. S. Tough et al. in Lancet 25 Feb. 411/2 In this paper the abnormal chromosome, for the sake of brevity, is referred to by the symbol Ph¹. This is chosen as it indicates the geographical location, Philadelphia in the United States, of the laboratories in which the chromosome was first noted, and thus it accords with the recommendations on the nomenclature of abnormal chromosomes of the Denver conference.]

1961 Lancet 25 Feb. 433/1 (heading) The Philadelphia chromosome.

1963 J. B. Walter & M. S. Israel Gen. Pathol. iii. 45 Some of the leucocytes show replacement of one of their small autosomes by a minute chromosome (the ‘Philadelphia chromosome’). This is generally assumed to be 21.

1977 R. B. Thompson Disorders of Blood xxxv. 566/1 The Philadelphia chromosome usually arises by a translocation from G22 to C9.

1984 J. R. Tighe & D. R. Davies Pathol. (ed. 4) viii. 62 The Philadelphia chromosome, is a constant abnormality in chronic myeloid leukaemia.

1993 New Scientist 22 May 37/2 Recently, biologists..discovered a role for imprinting in chronic myeloid leukaemia, a form of the disease where the leukaemic cells contain an unusual hybrid chromosome. This so-called Philadelphia chromosome consists of virtually the whole of chromosome 22 fused to a small section of chromosome 9.

2000 New Scientist 4 Nov. 50/1 It wasn't until the late 1990s that geneticists realised that Philadelphia chromosomes make cells cancerous because the mutation creates a new, active gene.

1977 Valley News (Van Nuys, Calif.) 18 Mar. 20/2 (advt.) Philadelphia cheesesteak sandwich. Tender slices of spencer steak smothered with onions, topped with melted cheese &..bell peppers. Served on a giant french roll.

1986 Washington Post 27 July (Mag. section) 23/1 Don't they know a Philadelphia Cheese Steak is drenched in Cheez Whiz?

1996 D. McCumber Playing Off the Rail viii. 198 I talked Tony into coming off his diet and having one of their incredible Philadelphia cheese steak sandwiches.