pharmacophoricadj.

Brit.

/ˌfɑːməkəˈfɒrɪk/, U.S.

/ˌfɑrməkəˈfɔrɪk/

Origin: Formed within English, by compounding. Etymons: pharmaco- comb. form, osmophoric adj.

Etymology: < pharmaco- comb. form + -phoric (in e.g. osmophoric adj.). Compare later pharmacophore n. Compare French pharmacophore (1956 or earlier).

Pharmacology.

Of the nature of, relating to, or involving a pharmacophore.

ΚΠ

1953 F. W. Schueler in Arch. Internat. de Pharmacodynamie et Thérapie 95 376 (title) The interaction of statistical and coulombic factors in the characterization of pharmacophoric moieties.

1963 M. B. Chenoweth & L. P. McCarty in Pharmacol. Rev. 15 673 The word ‘pharmacophoric’ parallels the constructions now used such as chromatophoric, osmophoric, etc., and is found in the medicinal chemistry literature. We will use it to mean a significant change produced by a halogen in the pharmacological activity of a molecule.

1984 Jrnl. Pharmacy & Pharmacol. 36 373 The tropane skeleton may be considered a useful pharmacophoric group in the design of new dopaminergic drugs.

2001 Jrnl. Medicinal Chem. 44 1530 A pharmacophoric model for searching new drug leads from small-molecule libraries.

This is a new entry (OED Third Edition, December 2002; most recently modified version published online March 2022).

单词	pharmacophoric
释义	pharmacophoricadj. Brit. /ˌfɑːməkəˈfɒrɪk/, U.S. /ˌfɑrməkəˈfɔrɪk/ Origin: Formed within English, by compounding. Etymons: pharmaco- comb. form, osmophoric adj. Etymology: < pharmaco- comb. form + -phoric (in e.g. osmophoric adj.). Compare later pharmacophore n. Compare French pharmacophore (1956 or earlier). Pharmacology. Of the nature of, relating to, or involving a pharmacophore. ΚΠ 1953 F. W. Schueler in Arch. Internat. de Pharmacodynamie et Thérapie 95 376 (title) The interaction of statistical and coulombic factors in the characterization of pharmacophoric moieties. 1963 M. B. Chenoweth & L. P. McCarty in Pharmacol. Rev. 15 673 The word ‘pharmacophoric’ parallels the constructions now used such as chromatophoric, osmophoric, etc., and is found in the medicinal chemistry literature. We will use it to mean a significant change produced by a halogen in the pharmacological activity of a molecule. 1984 Jrnl. Pharmacy & Pharmacol. 36 373 The tropane skeleton may be considered a useful pharmacophoric group in the design of new dopaminergic drugs. 2001 Jrnl. Medicinal Chem. 44 1530 A pharmacophoric model for searching new drug leads from small-molecule libraries. This is a new entry (OED Third Edition, December 2002; most recently modified version published online March 2022). < adj.1953
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