phocomelian.

Brit.

/ˌfəʊkə(ʊ)ˈmiːlɪə/, U.S.

/ˌfoʊkoʊˈmiliə/

Forms: 1800s– phocomelia, 1900s– phokomelia (rare).

Origin: A borrowing from Greek, combined with English elements; modelled on a French lexical item. Etymons: Greek ϕώκη , -o- connective, Greek μέλος , -ia suffix¹.

Etymology: < ancient Greek ϕώκη seal (see phoca n.) + -o- connective + ancient Greek μέλος limb (see melos n.) + -ia suffix¹, after French phocomélie (I. Geoffroy Saint-Hilaire Hist. des anomalies (1836) II. 209).With the form phokomelia compare German Phokomelie (1879 or earlier).

Medicine.

A congenital malformation in which the long bones of one or more limbs are absent or rudimentary, resulting in the hand or foot being attached close to the trunk.Phocomelia normally occurs as a rare and sporadic malformation, but a large number of cases resulted from the administration of thalidomide to pregnant women around 1960.

ΘΚΠ

the world > health and disease > ill health > deformity > [noun] > congenital union > of limbs

siren formation1831

phocomelia1837

sympodia1848

symmelia1901

1837 A. Jacob in Todd's Cycl. Anat. & Physiol. II. 171/2 An interesting case of Phocomelia is recorded by Dumeril; all the limbs were in this condition.

1872 Lancet 20 July 81/1 (heading) Phocomelia in a child of six months.

1932 H. Cummins in Practitioners Libr. Med. & Surg. I. i. 20 In phocomelia the extremity is abbreviated, through reduction or absence of the proximal and intermediate segments, the hands and feet approaching normal.

1947 Arch. Pathol. 44 521 The majority of the homozygous Creeper embryos die on the fourth day... Those which survive have phokomelia.

1968 Brit. Med. Bull. 24 207/1 The demonstration of an association between phocomelia and thalidomide.

1978 Sci. Amer. Oct. 130/3 The drug thalidomide could cause phocomelia..in a fetus when it was taken by a pregnant woman.

1991 Lancet 7 Sept. 639/2 Observational studies must be conducted and interpreted with care, but it is surely correct that some (e.g., those connecting smoking to lung cancer and those connecting thalidomide with phocomelia), provide fully convincing evidence for a causal connection.

2001 N.Y. Rev. Bks. 17 May 12/1 He was born with lower-body phocomelia after his mother was given thalidomide for nausea during pregnancy.

Derivatives

phocoˈmelous adj. rare = phocomelic adj.

ΚΠ

1902 Brit. Med. Jrnl. 15 Mar. 672 Whether the Harpy owes its origin to the occurrence of a phocomelous fetus.

1988 Italian Bks. & Periodicals 31 63/1 A phocomelous birth in Ravenna in 1512 and an abnormal twin conception in Bologna in 1514 rapidly spread as indisputable signs of heavenly threats.

This entry has been updated (OED Third Edition, March 2006; most recently modified version published online June 2022).

单词	phocomelia
释义	phocomelian. Brit. /ˌfəʊkə(ʊ)ˈmiːlɪə/, U.S. /ˌfoʊkoʊˈmiliə/ Forms: 1800s– phocomelia, 1900s– phokomelia (rare). Origin: A borrowing from Greek, combined with English elements; modelled on a French lexical item. Etymons: Greek ϕώκη , -o- connective, Greek μέλος , -ia suffix¹. Etymology: < ancient Greek ϕώκη seal (see phoca n.) + -o- connective + ancient Greek μέλος limb (see melos n.) + -ia suffix¹, after French phocomélie (I. Geoffroy Saint-Hilaire Hist. des anomalies (1836) II. 209).With the form phokomelia compare German Phokomelie (1879 or earlier). Medicine. A congenital malformation in which the long bones of one or more limbs are absent or rudimentary, resulting in the hand or foot being attached close to the trunk.Phocomelia normally occurs as a rare and sporadic malformation, but a large number of cases resulted from the administration of thalidomide to pregnant women around 1960. ΘΚΠ the world > health and disease > ill health > deformity > [noun] > congenital union > of limbs siren formation1831 phocomelia1837 sympodia1848 symmelia1901 1837 A. Jacob in Todd's Cycl. Anat. & Physiol. II. 171/2 An interesting case of Phocomelia is recorded by Dumeril; all the limbs were in this condition. 1872 Lancet 20 July 81/1 (heading) Phocomelia in a child of six months. 1932 H. Cummins in Practitioners Libr. Med. & Surg. I. i. 20 In phocomelia the extremity is abbreviated, through reduction or absence of the proximal and intermediate segments, the hands and feet approaching normal. 1947 Arch. Pathol. 44 521 The majority of the homozygous Creeper embryos die on the fourth day... Those which survive have phokomelia. 1968 Brit. Med. Bull. 24 207/1 The demonstration of an association between phocomelia and thalidomide. 1978 Sci. Amer. Oct. 130/3 The drug thalidomide could cause phocomelia..in a fetus when it was taken by a pregnant woman. 1991 Lancet 7 Sept. 639/2 Observational studies must be conducted and interpreted with care, but it is surely correct that some (e.g., those connecting smoking to lung cancer and those connecting thalidomide with phocomelia), provide fully convincing evidence for a causal connection. 2001 N.Y. Rev. Bks. 17 May 12/1 He was born with lower-body phocomelia after his mother was given thalidomide for nausea during pregnancy. Derivatives phocoˈmelous adj. rare = phocomelic adj. ΚΠ 1902 Brit. Med. Jrnl. 15 Mar. 672 Whether the Harpy owes its origin to the occurrence of a phocomelous fetus. 1988 Italian Bks. & Periodicals 31 63/1 A phocomelous birth in Ravenna in 1512 and an abnormal twin conception in Bologna in 1514 rapidly spread as indisputable signs of heavenly threats. This entry has been updated (OED Third Edition, March 2006; most recently modified version published online June 2022). < n.1837
随便看	θ157914 θ157915 θ157916 θ157917 θ157918 θ157919 θ15792 θ157920 θ157921 θ157922 θ157923 θ157924 θ157925 θ157926 θ157927 θ157928 θ157929 θ15793 θ157930 θ157931 θ157932 θ157933 θ157934 θ157935 θ157936