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单词 phosphorylase
释义

phosphorylasen.

Brit. /ˈfɒsfərᵻleɪz/, /fɒsˈfɒrᵻleɪz/, U.S. /fɑsˈfɔrəˌleɪz/, /ˈfɑsfərəˌleɪz/, /fɑsˈfɔrəˌleɪs/, /ˈfɑsfərəˌleɪs/
Origin: Formed within English, by derivation. Etymons: phosphoryl n., -ase suffix.
Etymology: < phosphoryl n. + -ase suffix. Compare French phosphorylase (1943 or earlier).
Biochemistry.
Any of a group of enzymes which bring about phosphorolysis, as in the breakdown of glucose polysaccharides to produce glucose phosphate. Frequently with distinguishing word, indicating the substrate.
ΘΚΠ
the world > life > biology > substance > process stimulators or inhibitors > other stimulators or inhibitors > [noun]
styptica1400
carrier1844
luciferase1888
luciferin1888
urease1892
peroxidase1899
protease1903
renin1903
phenolase1907
proteinase1907
phytase1908
lecithinase1910
uricase1910
phosphatase1912
prunase1912
phenoloxidase1913
oxytocin1927
phosphomonoesterase1932
androgen1936
phosphorylase1939
slow reacting substance1939
phospholipase1945
plasmin1945
bradykinin1949
nitroreductase1953
cytostatic1964
oncogen1967
autoinducer1968
1939 G. T. Cori et al. in Jrnl. Biol. Chem. 127 771 Various mammalian tissues..contain an enzyme which can be extracted with water and which forms glucose-1-phosphoric ester..from glycogen and inorganic phosphate... This enzyme, which will be referred to as phosphorylase, initiates the degradation of glycogen.
1955 Sci. News Let. 7 May 297/1 Use of muscle to do work and its recovery depends upon the chemical action of an enzyme, phosphorylase, which is found in muscle.
1971 Nature 19 Feb. 529/1 The breakdown of glycogen..is controlled by the activity of glycogen phosphorylase. This enzyme exists in two states: phosphorylase b..is a form of low concentration... Under the action of phosphorylase kinase it is phosphorylated at one serine residue in each of the four subunits, to give the highly active phosphorylase a.
1989 Jrnl. Developmental Physiol. 11 361/2 Phosphorylase activity was assayed in the direction of glycogen synthesis.
2000 Isis 91 731 Polynucleotide phosphorylase was acknowledged both as an important enzymological achievement and because it became a tool for elucidating the genetic code.
This entry has been updated (OED Third Edition, March 2006; most recently modified version published online March 2022).
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n.1939
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