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单词 phrenosin
释义

phrenosinn.

Brit. /ˈfrɛnəsɪn/, U.S. /ˈfrɛnəs(ə)n/
Forms: 1800s– phrenosin, 1800s– phrenosine.
Origin: Formed within English, by derivation. Etymons: phreno- comb. form, -ose suffix2, -in suffix1.
Etymology: < phreno- comb. form + -ose suffix2 + -in suffix1 (see quot. 1878). Compare German Phrenosin (1881 or earlier).
Biochemistry.
A cerebroside, C48H93NO9, which on hydrolysis yields galactose, sphingosine, and a long-chain alpha-hydroxy fatty acid.
ΚΠ
1878 C. T. Kingzett Animal Chem. xv. 305 To the first of these Thudichum reserves the name of cerebrine, the second he terms phrenosine, and the third kerasine.
1881 J. L. W. Thudichum in Proc. Royal Soc. 31 284 Those bodies—the kephalines, myelins, lecithins, phrenosins, kerasins, and cerebrinic acid, which I claim as true immediate principles of the brain.
1915 Science 16 July 89/2 Rosenheim by a determination of the optical characters..of phrenosin and kerasin, obtained from the brain, succeeded in differentiating these two substances.
1953 A. G. E. Pearse Histochem. vii. 134 The cerebrosides, represented chiefly by phrenosin and kerasin,..occur in tissues outside as well as within the central nervous system.
1990 Biochemistry 29 3895/2 The biexponential kinetics..for the transfer of kerasin and phrenosin..reflect the presence of..long and short acyl chain species in these bovine brain ceramides.
This entry has been updated (OED Third Edition, March 2006; most recently modified version published online March 2022).
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n.1878
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