plasminogenn.

1945 L. R. Christensen & C. M. Macleod in Jrnl. Gen. Physiol. 28 581 The inactive enzyme as it occurs in serum and plasma may be designated as ‘plasminogen’ to indicate its source, the plasma, and also to indicate that it is in an inactive, precursor state.

1976 Nature 22 Jan. 235/2 Plasminogen is the plasma proenzyme which, on conversion to its active form, plasmin, is considered responsible for lysis of fibrin deposits resulting from physiological or pathological activation of the coagulation cascade.

1990 Protein Engin. 4 191/1 The fibrin degradation is accomplished by plasmin, a relatively aspecific protease occurring in plasma as an inactive proenzyme, plasminogen.

1953 Proc. Soc. Exper. Biol. & Med. 82 265/1 The demonstration of a plasminogen activator in spontaneously active human blood.

1964 A. White et al. Princ. Biochem. (ed. 3) xxxiii. 655 Plasminogen activator also is produced in blood vessel walls, from which it is released on vascular injury.

1992 Sci. Amer. June 28/2 Under the appropriate conditions, such as those found at the sites of healing wounds, enzymes called plasminogen activators alter part of the plasminogen molecule and turn on its fibrin-cutting activity.