polykaryocyten.
/ˌpɒlɪˈkarɪə(ʊ)sʌɪt/, U.S. /ˌpɑliˈkɛrioʊˌsaɪt/ Biology and Medicine.
A multinucleated giant cell; (in early use) spec. an osteoclast (now rare).
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the world > life > the body > structural parts > bone or bones > substance of bones > [noun] > cell or corpuscle of
bone corpuscle1842
bone cell1846
myeloplax1866
osteoblast1867
astroblast1871
osteoclast1872
myeloplaque1877
polykaryocyte1890
myeloplast1891
astrocyte1893
osteocyte1918
1890 W. H. Howell in Jrnl. Morphol. 4 118 The first class might be named polykaryocytes, or multinucleated giant cells.
1946 Blood 1 29 Morone sharply differentiated the polykaryocytes from osteoclasts, but in this he was disputed by Lambin and Lamers.
1968 E. Kelemen Physiopathol. & Therapy Human Blood Dis. (1969) i. 36 Even larger cells, resembling megakaryocytes, are the osteoclasts or polykaryocytes. These two cells have to do with bone formation and are more often seen in a trephine biopsy.
1983 Exper. & Molecular Pathol. 38 398 Polycaryocytes comprised of cells of the internal granular layer of the cerebellum were observed in some animals inoculated with HSV1.
2004 Virology 328 244 Small polykaryocytes resulting from cell fusion are found in herpes simplex virus (HSV) lesions in patients, but their significance for viral spread and pathogenesis is unclear.
This entry has been updated (OED Third Edition, September 2006; most recently modified version published online March 2022).
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n.1890