porphobilinn.
/ˌpɔːfəʊˈbʌɪlɪn/, U.S. /ˌpɔrfoʊˈbaɪlɪn/ Biochemistry.
Any of a group of red-brown pigments derived from porphobilinogen.
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porphobilin1939
ommatin1940
ommin1940
ommochrome1945
1939 Chem. Abstr. 33 8777/1 Boiling in acid destroys I by conversion to a red porphobilin (II) with a mol. wt. of 750 to 800.
1952 Science 2 May 496/2 Solutions of porphobilinogen obtained by the above method, after having been acidified to pH 4·0 and boiled for 30 min, gave rise only to porphobilin, a dark-brown pigment without characteristic absorption spectrum or any porphyrin characteristics.
1964 A. White et al. Princ. Biochem. (ed. 3) xlii. 793 The urine darkens markedly on standing, because of the conversion of abnormal quantities of porphyrinogens and other heme precursors into porphyrins, porphobilins, and other unidentified pigments.
2000 Chemist & Druggist (Nexis) 15 Apr. 1 In an acute attack [of porphyria], urine when passed becomes dark on standing, due to porphobilinogen..polymerising to uroporphyrin and a brownish-red pigment porphobilin.
This entry has been updated (OED Third Edition, December 2006; most recently modified version published online March 2022).
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n.1939