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单词 prazosin
释义

prazosinn.

Brit. /ˈpreɪzə(ʊ)sɪn/, U.S. /ˈpreɪzəs(ə)n/
Origin: Perhaps formed within English, by derivation. Etymons: piperazine n., -o- connective, -in suffix1.
Etymology: Perhaps < p- and -raz- (in piperazine n.) + -o- connective + -in suffix1, with apparently arbitrary insertion of -s-.
Pharmacology.
An alpha blocker used chiefly as a smooth muscle relaxant, esp. in the treatment of hypertension and benign prostatic hyperplasia.Prazosin is a tetracyclic compound incorporating quinazoline, piperazine, and furan rings; C19H21N5O4.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders
Neo-Synephrine1934
Priscol1938
phenylephrine1947
hexamethonium1949
Priscoline1949
methonium1950
hydralazine1952
phentolamine1953
methyldopa1954
pentolinium1954
mecamylamine1955
hydrochlorothiazide1958
pempidine1958
guanethidine1959
hydroflumethiazide1959
thiazide1959
pheniprazine1960
pargyline1961
vasodepressor1961
alpha blocker1965
clonidine1969
prazosin1970
timolol1973
1970 Jrnl. Clin. Pharmacol. 10 417/1 These data suggest that prazosin hydrochloride is an efficacious agent for the therapy of ambulatory patients with arterial hypertension.
1980 Lancet 5 Apr. 735/2 We treated a group of patients with severe heart-failure with a vasodilator, prazosin.
2004 R. Anderson Home Front 186 The drug prazosin is already helping transform the lives of some veterans.
This entry has been updated (OED Third Edition, March 2007; most recently modified version published online March 2022).
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n.1970
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