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单词 promazine
释义

promazinen.

Brit. /ˈprəʊməziːn/, /ˈprɒməziːn/, U.S. /ˈprɑməˌzin/
Origin: Formed within English, by clipping or shortening. Etymon: chlorpromazine n.
Etymology: < -promazine (in chlorpromazine n.). Compare French promazine (dated c1955 in Robert Dict. alphabétique et analogique (1986)).
Pharmacology.
A drug of the phenothiazine class, used as a tranquillizer and antipsychotic. Also: any of a group of compounds structurally related to this. Cf. earlier chlorpromazine n.Chemical name: 10-(3-dimethylaminopropyl)phenothiazine; C17H20N2S.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > tranquillizer > specific substances or preparations
nepenthes1580
nepenthe1595
Seconal1935
secobarbital1950
mephenesin1952
Largactil1953
Miltown1954
meprobamate1955
hydroxyzine1956
promazine1956
Sparine1956
prochlorperazine1957
Stelazine1958
trifluoperazine1958
Prolixin1959
chlordiazepoxide1960
Librium1960
diazepam1961
Valium1961
oxazepam1964
pimozide1968
lorazepam1969
temazepam1970
alprazolam1973
1956 Jrnl. Amer. Med. Assoc. 5 May 45/1 Treatment with promazine satisfactorily relieved the withdrawal symptoms of acute alcoholic intoxication.
1971 B. R. Jones Pharmacol. iii. 15 Post~operative vomiting is reduced by including in the premedication an intramuscular injection of either an antihistamine..or a tranquillizer of the phenothiazine type such as Promazine.
1998 Jrnl. Medicinal Chem. 41 148 Analogues [of phenothiazine], synthesized to define structure-activity relationships for the active site, included N-acylpromazines, 2-substituted phenothiazines, and trisubstituted promazines.
This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).
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n.1956
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