procainen.
/ˈprəʊkeɪn/, U.S. /ˈproʊˌkeɪn/ Pharmacology.
A local anaesthetic administered chiefly by injection.Chemical name: 4-aminobenzoic acid 2-(dimethylamino)-ethyl ester; NH2C6H4·COO·CH2CH2N(C2H5)2.A brand name for this drug is novocaine.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > anaesthetic > [noun] > local > specific drugs
cocaine1874
drumine1886
eucaine1896
stovaine1904
alypin1905
novocaine1905
procaine1918
Nupercaine1929
Percaine1930
pantocaine1931
pontocaine1935
tetracaine1943
xylocaine1946
cinchocaine1947
lidocaine1949
Anectine1950
succinylcholine1950
Scoline1952
suxamethonium1953
lignocaine1954
1918 Jrnl. Amer. Med. Assoc. 23 Feb. 537/2 Procaine is the official name of the product introduced as novocaine.
1940 H. A. McGuigan Appl. Pharmacol. 536 The activity of procaine is increased by the addition of 0·25 per cent sodium bicarbonate or 0·50 per cent potassium sulfate to the solution injected.
1976 H. Ferguson Confessions Long Distance Acid Head 7 Apart from cannabis, I have used barbiturates,..morphine, cocaine, procaine, ritalin, even apomorphine once.
1987 E. W. Burr Compan. Bird Med. xxiii. 148/2 Procaine has had limited usage because many avian patients are very sensitive to its application.
Compounds
procaine penicillin n. a salt of procaine and benzylpenicillin, administered by intramuscular injection to provide prolonged release of the benzylpenicillin, esp. in the treatment of gonorrhoea and syphilis.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > antibiotics > [noun] > penicillin > other penicillin antibiotics
citrinin1931
griseofulvin1939
patulin1943
procaine penicillin1949
celbenin1960
methicillin1961
amoxicillin1971
1947 Proc. Staff Meetings Mayo Clinic 22 567 The preparation is a procaine salt of penicillin G (duracillin) which was prepared in the research laboratories of Eli Lilly and Company. Procaine penicillin G is a crystalline, nonpyrogenic substance which is prepared by combining one molecule of procaine base..with a molecule of penicillin.]
1949 Florey & Jennings in H. W. Florey et al. Antibiotics II. xxxvii. 1220 The first accounts of trials with procaine penicillin in man all mentioned the freedom of patients from local or general toxic effects.
1967 Martindale's Extra Pharmacopoeia (ed. 25) 1007/2 Procaine penicillin is administered by intramuscular injection to create a depot from which penicillin is slowly liberated.
1993 Equus July 24/2 My 15-year-old mare recently experienced an allergic reaction to procaine penicillin.
This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).
<
n.1918